Effectiveness of Structural-Level Needle/Syringe Programs to Reduce HCV and HIV Infection Among People Who Inject Drugs: A Systematic Review

Details

• Alternative Title:
  AIDS Behav
• Personal Author:
  Abdul-Quader, Abu S. ; Feelemyer, Jonathan ; Modi, Shilpa ; Stein, Ellen S. ; Briceno, Alya ; Semaan, Salaam ; Horvath, Tara ; Kennedy, Gail E. ; Des Jarlais, Don C.
• Description:
  Needle-syringe programs (NSP) have been effective in reducing HIV and hepatitis C (HCV) infection among people who inject drugs (PWID). Achieving sustainable reductions in these blood-borne infections requires addressing structural factors so PWID can legally access NSP services. Systematic literature searches collected information on NSP coverage and changes in HIV or HCV infection prevalence or incidence at the population level. Included studies had to document biomarkers (HIV or HCV) coupled with structural-level NSP, defined by a minimum 50 % coverage of PWID and distribution of 10 or more needles/syringe per PWID per year. Fifteen studies reported structural-level NSP and changes in HIV or HCV infection prevalence/incidence. Nine reported decreases in HIV prevalence, six in HCV infection prevalence, and three reported decreases in HIV incidence. The results support NSP as a structural-level intervention to reduce population-level infection and implementation of NSP for prevention and treatment of HIV and HCV infection.
• Subjects:
  Communicable Disease Control Female Harm Reduction Health Knowledge, Attitudes, Practice Hepatitis C HIV Infections Humans Male Needle-Exchange Programs Prevalence Program Evaluation Public Health Randomized Controlled Trials As Topic Risk-Taking Substance Abuse, Intravenous

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• Keywords:
  Chlorination HIV Household Water Treatment Needle-exchange Programs People Who Inject Drugs (PWID) Safe Water Storage Structural-level Interventions
• Source:
  AIDS Behav. 17(9):2878-2892
• Pubmed ID:
  23975473
• Pubmed Central ID:
  PMC6509353
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; R01 AI083035/AI/NIAID NIH HHSUnited States/ ; R01 AI 083035/AI/NIAID NIH HHSUnited States/
• Volume:
  17
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:302c48f8f00922c69f51b97a2d2514b024453a1f3493903eb5a637f37253e44d
• Download URL:
  https://stacks.cdc.gov/view/cdc/78403/cdc_78403_DS1.pdf
• File Type:
  [PDF - 1007.61 KB ]