Trends in anogenital wart incidence among Tennessee Medicaid enrollees, 2006–2014: The impact of human papillomavirus vaccination

Details

• Alternative Title:
  Papillomavirus Res
• Personal Author:
  Shing, Jaimie Z. ; Hull, Pamela C. ; Zhu, Yuwei ; Gargano, Julia W. ; Markowitz, Lauri E. ; Cleveland, Angela A. ; Pemmaraju, Manideepthi ; Park, Ina U. ; Whitney, Erin ; Mitchel, Edward F. ; Griffin, Marie R.
• Description:
  Introduction
  
  Evidence of human papillomavirus (HPV) vaccine impact on anogenital warts (AGWs) by race or urbanicity in the US is lacking. We evaluated HPV vaccine impact in Tennessee by assessing AGW trends among Tennessee Medicaid (TennCare) enrollees aged 15–39 years from 2006-2014.
  
  Methods
  
  Persons with incident AGWs were identified using diagnosis/pharmacy codes from TennCare billing claims. We calculated sex-specific annual AGW incidence by age group, race, and urbanicity; estimated annual percent changes (APCs) using log-linear models; and performed pairwise comparisons by race and urbanicity.
  
  Results
  
  AGW incidence decreased among females aged 15–19 (APC = −10.6; P < 0.01) and 20–24 years (APC = −3.9; P = 0.02). Overall trends were similar between Whites and Blacks, and between those living in metropolitan statistical areas (MSAs) and non-MSAs. Rates among males aged 15–19 years began decreasing after 2010. Among enrollees aged 25–39 years, rates increased or were stable.
  
  Conclusions
  
  Following introduction of the HPV vaccine in 2006, AGWs decreased among age groups most likely to be vaccinated. The change in trend among young males after 2010 suggests early herd effects. Our findings indicate vaccine effects and support the importance of improving adherence to current vaccination recommendations for preventing AGWs and other HPV-related diseases.
  
  
• Subjects:
  Adolescent Adult Age Factors Anus Diseases Condylomata Acuminata Female Humans Incidence Male Medicaid Papillomavirus Vaccines Race Factors Young Adult

  More +
• Source:
  Papillomavirus Res. 2019; 7:141-149
• Pubmed ID:
  30980966
• Pubmed Central ID:
  PMC6468146
• Document Type:
  Journal Article
• Funding:
  TL1 TR002244/TR/NCATS NIH HHS/United States
• Place as Subject:
  Tennessee
• Volume:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b636bdbcf15c7b7607abbfa20ef5839d86004a3fa8a4dcc2edd518d58207fe34
• Download URL:
  https://stacks.cdc.gov/view/cdc/78193/cdc_78193_DS1.pdf
• File Type:
  [PDF - 2.04 MB ]