Alligators as West Nile Virus Amplifiers

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Klenk, Kaci ; Snow, Jamie ; Morgan, Katrina ; Bowen, Richard ; Stephens, Michael ; Foster, Falicia ; Gordy, Paul ; Beckett, Susan ; Komar, Nicholas ; Gubler, Duane ; Bunning, Michel
• Description:
  Recent evidence suggests that American alligators (Alligator mississippiensis) may be capable of transmitting West Nile virus (WNV) to other alligators. We experimentally exposed 24 juvenile alligators to WNV parenterally or orally. All became infected, and all but three sustained viremia titers >5.0 log10 PFU/mL (a threshold considered infectious for Culex quinquefasciatus mosquitoes) for 1 to 8 days. Noninoculated tankmates also became infected. The viremia profiles and multiple routes of infection suggest alligators may play an important role in WNV transmission in areas with high population densities of juvenile alligators.
• Subjects:
  Alligators And Crocodiles Animals Antibodies, Viral Disease Reservoirs Environment Research Temperature Viral Load Viremia Virus Replication
• Source:
  Emerg Infect Dis. 10(12):2150-2155.
• Document Type:
  Journal Article
• Volume:
  10
• Issue:
  12
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:fefbb4c7aaab83021dbab12ccdc7880815a2159409b126c49d9a23a215db0514
• Download URL:
  https://stacks.cdc.gov/view/cdc/7794/cdc_7794_DS1.pdf
• File Type:
  [PDF - 139.72 KB ]