i
surveillance estimates
-
November 22 2018
Source: Ann Epidemiol. 31:3-7
[PDF-75.73 KB]
Details:
-
Alternative Title:Ann Epidemiol
-
Personal Author:
-
Description:Purpose:
To assess sampling bias in national viral suppression (VS) estimates derived from the Medical Monitoring Project (MMP) resulting from use of an abbreviated (four-month) annual sampling period. We aimed to improve VS estimates using cohort data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) and a novel cohort-adjustment method.
Methods:
Using full calendar years of NA-ACCORD data, we assessed timing of HIV care attendance (inside versus exclusively outside MMP’s four-month sampling period), VS status at last test (<200 vs. ≥200 copies/mL), and associated demographics. These external estimates were used to standardize MMP to NA-ACCORD data with multivariable regression models of care attendance andVS, yielding adjusted 2009–2013 VS estimates with 95% confidence intervals (CI).
Results:
Weighted percentages of VS among persons in HIV care were 67% in 2009 and 77% in 2013. These estimates are slightly lower than previously published MMP estimates (72% and 80% in 2009 and 2013, respectively). The number of persons receiving HIV care was previously underestimated by 20%, because patients receiving care exclusively outside the MMP sampling period did not contribute toward the weighted population estimate.
Conclusions:
Careful examination of national surveillance estimates using data triangulation and novel methodologies can improve the robustness of VS estimates.
-
Subjects:
-
Source:
-
Pubmed ID:30529086
-
Pubmed Central ID:PMC6420358
-
Document Type:
-
Funding:
-
Place as Subject:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
Email
CDC-INFO
