Relationships among organ damage, social support, and depression in African American women with systemic lupus erythematosus

Jordan, J; Thompson, NJ; Dunlop-Thomas, C; Lim, S Sam; Drenkard, C

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Relationships among organ damage, social support, and depression in African American women with systemic lupus erythematosus

Nov 27 2018
By Jordan, J ; Thompson, NJ ; Dunlop-Thomas, C ; ...
Source: Lupus. 28(2):253-260

[PDF-316.63 KB]

English

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Details:

Alternative Title:

Lupus
Personal Author:

Jordan, J ; Thompson, NJ ; Dunlop-Thomas, C ; Lim, S Sam ; Drenkard, C

Jordan, J ; Thompson, NJ ; Dunlop-Thomas, C ; Lim, S Sam ; Drenkard, C Less -
Description:

Objectives:

Systemic lupus erythematosus (SLE) disproportionately strikes African American women. Social support can potentially reduce disease impact. The purpose of this study is to understand the relationship between organ damage and depression in African American women and how social support influences this relationship.

Methods:

We used a mixed methods design, analyzing self-reported data on lupus-related organ damage, depression, and social support in 437 African American women with SLE recruited in the Georgians Organized Against Lupus (GOAL) cohort. Moreover, we conducted interviews among 15 GOAL participants to gather patients’ perspectives about the role of social support in people who live with lupus.

Results:

We found a significant association between organ damage and depression (r = 0.163, p = 0.001), as well as between depression and social support (F = 17.574, p<0.001). The quantitative analysis did not render social support as a significant moderator in the organ damage–depression relationship. Interviews, however, revealed that African American women with the most severe organ damage have the greatest need for support.

Conclusions:

Social support is a key resource for lupus patients with high disease burden. Overall, these findings highlight the importance of monitoring depressive symptoms in this population and developing interventions aimed to increase social support available to lupus patients. Lupus (2019) 28, 253–260.
Subjects:

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African American Article Depression Lupus Organ Damage Social Support Systemic Lupus Erythematosus
Source:

Lupus. 28(2):253-260
Pubmed ID:

30482093
Pubmed Central ID:

PMC6415670
Document Type:

Journal Article
Funding:

U01 DP005119/DP/NCCDPHP CDC HHS/United States ; U01DP005119/ACL HHS/United States

U01 DP005119/DP/NCCDPHP CDC HHS/United States ; U01DP005119/ACL HHS/United States Less -
Volume:

28
Issue:

2
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:72b726bb0ba4d96f98212883564b533d8300e119867e4a5da93de2220ecb0b80
Download URL:

https://stacks.cdc.gov/view/cdc/76930/cdc_76930_DS1.pdf
File Type:

nihms-1015666.nxml

xml

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