Undeclared Formaldehyde Levels in Patient Consumer Products: Formaldehyde Test Kit Utility

Details

• Alternative Title:
  Cutan Ocul Toxicol
• Personal Author:
  Ham, Jason E. ; Siegel, Paul ; Maibach, Howard
• Description:
  Formaldehyde allergic contact dermatitis (ACD) may be due to products with free formaldehyde or formaldehyde-releasing agents; however, assessment of formaldehyde levels in such products is infrequently conducted. The present study quantifies total releasable formaldehyde from "in-use" products associated with formaldehyde ACD and tests the utility of commercially available formaldehyde spot test kits.|Personal care products from 2 patients with ACD to formaldehyde were initially screened at the clinic for formaldehyde using a formaldehyde spot test kit. Formaldehyde positive products were sent to the laboratory for confirmation by gas chromatography-mass spectrometry. In addition, 4 formaldehyde spot test kits were evaluated for potential utility in a clinical setting.|Nine of the 10 formaldehyde spot test kit positive products obtained from formaldehyde allergic patients had formaldehyde with total releasable formaldehyde levels ranging from 5.4 to 269.4 µg/g. Of these, only two shampoos tested listed a formaldehyde-releasing agent in the ingredients or product literature. Subsequently, commercially available formaldehyde spot test kits were evaluated in the laboratory for ability to identify formaldehyde in personal care products.|Chemical based formaldehyde spot test were more reliable than the enzymatic based test in identifying product releasable formaldehyde content. It is concluded that product labeled ingredient lists and available information are often inadequate to confirm the potential for formaldehyde exposure and chemical based spot test kits may have utility for identification of potential formaldehyde exposure from personal care products.
• Subjects:
  Allergic Contact Dermatitis Article Formaldehyde Formaldehyde-Releaser Formaldehyde Spot Test Kit
• Source:
  Cutan Ocul Toxicol. 38(2):112-117
• Pubmed ID:
  29719992
• Pubmed Central ID:
  PMC6389437
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  38
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d0da17d5a328ddb9361dbd5f3484a48aa5bb2e72354201760ce76edc670195a1
• Download URL:
  https://stacks.cdc.gov/view/cdc/76180/cdc_76180_DS1.pdf
• File Type:
  [PDF - 324.06 KB ]