Preventing tetanus, diphtheria, and pertussis among adolescents; use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines : recommendations of the Advisory Committee on Immunization Practices (ACIP)

Broder, Karen R.; Cortese, Margaret M.; Iskander, John K.; Kretsinger, Katrina; Slade, Barbara A.; Brown, Kristin H.; Mijalski, Christina M.; Tiwari, Tejpratap; Weston, Emily J.; Cohn, Amanda C.; Srivastava, Pamela U.; Moran, John S.; Schwartz, Benjamin; Murphy, Trudy V.

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Preventing tetanus, diphtheria, and pertussis among adolescents; use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines : recommendations of the Advisory Committee on Immunization Practices (ACIP)

March 24, 2006
By Broder, Karen R. ; Cortese, Margaret M. ; Iskander, John K. ; ...
Source: MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 2006; 55(RR-3):1-34.
Series: MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 55, no. RR-3

[PDF-473.05 KB]

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Personal Author:

Broder, Karen R. ; Cortese, Margaret M. ; Iskander, John K. ; Kretsinger, Katrina ; Slade, Barbara A. ; ... More +

Broder, Karen R. ; Cortese, Margaret M. ; Iskander, John K. ; Kretsinger, Katrina ; Slade, Barbara A. ; Brown, Kristin H. ; Mijalski, Christina M. ; Tiwari, Tejpratap ; Weston, Emily J. ; Cohn, Amanda C. ; Srivastava, Pamela U. ; Moran, John S. ; Schwartz, Benjamin ; Murphy, Trudy V. Less -
Corporate Authors:

United States. Advisory Committee on Immunization Practices. ; Centers for Disease Control and Prevention (U.S.). Immunization Safety Office. ; National Immunization Program (Centers for Disease Control and Prevention). Epidemiology and Surveillance Division.

United States. Advisory Committee on Immunization Practices. ; Centers for Disease Control and Prevention (U.S.). Immunization Safety Office. ; National Immunization Program (Centers for Disease Control and Prevention). Epidemiology and Surveillance Division. Less -
Description:

During spring 2005, two tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) products formulated for use in adolescents (and, for one product, use in adults) were licensed in the United States (BOOSTRIX, GlaxoSmithKline Biologicals, Rixensart, Belgium [licensed May 3, 2005, for use in persons aged 10-18 years], and ADACEL, sanofi pasteur, Toronto, Ontario, Canada [licensed June 10, 2005, for use in persons aged 11-64 years]). Prelicensure studies demonstrated safety and efficacy against tetanus, diphtheria, and pertussis when Tdap was administered as a single booster dose to adolescents. To reduce pertussis morbidity in adolescents and maintain the standard of care for tetanus and diphtheria protection, the Advisory Committee on Immunization Practices (ACIP) recommends that: 1) adolescents aged 11-18 years should receive a single dose of Tdap instead of tetanus and diphtheria toxoids vaccine (Td) for booster immunization against tetanus, diphtheria, and pertussis if they have completed the recommended childhood diphtheria and tetanus toxoids and whole cell pertussis vaccine (DTP)/ diphtheria and tetanus toxoids and acellular pertussis vaccine (DTaP) vaccination series (five doses of pediatric DTP/DTaP before the seventh birthday; if the fourth dose was administered on or after the fourth birthday, the fifth dose is not needed) and have not received Td or Tdap. The preferred age for Tdap vaccination is 11-12 years; 2) adolescents aged 11-18 years who received Td, but not Tdap, are encouraged to receive a single dose of Tdap to provide protection against pertussis if they have completed the recommended childhood DTP/DTaP vaccination series. An interval of at least 5 years between Td and Tdap is encouraged to reduce the risk for local and systemic reactions after Tdap vaccination. However, an interval less than 5 years between Td and Tdap can be used; and 3) vaccine providers should administer Tdap and tetravalent meningococcal conjugate vaccine (Menactra, sanofi pasteur, Swiftwater, Pennsylvania) to adolescents aged 11-18 years during the same visit if both vaccines are indicated and available. This statement 1) reviews tetanus, diphtheria and pertussis vaccination policy in the United States, with emphasis on adolescents; 2) describes the clinical features and epidemiology of pertussis among adolescents; 3) summarizes the immunogenicity, efficacy, and safety data of the two Tdap vaccines licensed for use among adolescents; and 4) presents recommendations for tetanus, diphtheria, and pertussis vaccination among adolescents aged 11-18 years.
Content Notes:

prepared by Karen R. Broder, Margaret M. Cortese, John K. Iskander, Katrina Kretsinger, Barbara A. Slade, Kristin H. Brown, Christina M. Mijalski, Tejpratap Tiwari, Emily J. Weston, Amanda C. Cohn, Pamela U. Srivastava, John S. Moran, Benjamin Schwartz, Trudy V. Murphy

The material in this report originated in the National Immunization Program, Anne Schuchat, MD, Director, Epidemiology and Surveillance Division, Alison Mawle, PhD, Acting Director; and the Office of the Chief Science Officer, Dixie E. Snider, MD, Chief Science Officer, Immunization Safety Office, Frank DeStefano, MD, Acting Director.

Includes bibliographical references (p. 29-34).

JCSmith

1/13/2014
Subjects:

[+]

Diphtheria-Tetanus-acellular Pertussis Vaccines Diphtheria-Tetanus-Pertussis Vaccine/administration & Dosage Diphtheria/epidemiology Diphtheria/prevention & Control Immunization, Secondary/standards Immunization Schedule Tetanus Vaccination Whooping Cough
Source:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports / Centers for Disease Control. 2006; 55(RR-3):1-34.
Series:

MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 55, no. RR-3
Document Type:

Journal Issue
Genre:

Practice Guideline
Place as Subject:

United States
Pages in Document:

print; 43 p. : ill. ; 28 cm.
Volume:

55
Collection(s):

Advisory Committee on Immunization Practices (ACIP) Stephen B. Thacker CDC Library collection Morbidity and Mortality Weekly Report (MMWR) Guidelines and Recommendations
Main Document Checksum:

[+]

urn:sha256:10b06466fd87a9b34389164903d5f10042817aa9532276d9574199e2efd4a690
Download URL:

https://stacks.cdc.gov/view/cdc/6752/cdc_6752_DS1.pdf
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Preventing tetanus, diphtheria, and pertussis among adolescents; use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccines : recommendations of the Advisory Committee on Immunization Practices (ACIP)

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