Cyclosporine treatment of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report and brief review of the literature

Details

• Alternative Title:
  Pract Dermatol
• Personal Author:
  Kuschel, Stephanie L. ; Reedy, Matthew S.
• Description:
  Systemic corticosteroids are often considered the treatment of choice in the management of severe drug-induced hypersensitivity syndrome (DIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, in instances when systemic steroids are contraindicated, when there is an inadequate response to steroids, or when a prolonged course of steroids is not ideal, alternate therapies may be considered. Cyclosporine has been reported as a successful alternative immunosuppressive therapy; however, only a few cases have been reported in the literature. This observational case report presents an instance where cyclosporine was successfully used to treat DRESS syndrome in a patient where systemic steroids were ineffective.
• Subjects:
  Article Cyclosporine Drug-induced Hypersensitivity Syndrome Drug Reaction With Eosinophilia And Systemic Symptoms
• Source:
  Pract Dermatol. 2018:41-43
• Pubmed ID:
  30574026
• Pubmed Central ID:
  PMC6298437
• Document Type:
  Journal Article
• Funding:
  U2G PS000804/PS/NCHHSTP CDC HHS/United States
• Volume:
  2018
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c2f6549e2b2d5d7e89e556e0b0904f1c5a77fd47d4b5e539e8d5653d931c0644
• Download URL:
  https://stacks.cdc.gov/view/cdc/61494/cdc_61494_DS1.pdf
• File Type:
  [PDF - 544.20 KB ]