Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Brown, Allison C. ; Chen, Jessica C. ; Watkins, Louise K. Francois ; Campbell, Davina ; Folster, Jason P. ; ... More +
Brown, Allison C. ; Chen, Jessica C. ; Watkins, Louise K. Francois ; Campbell, Davina ; Folster, Jason P. ; Tate, Heather ; Wasilenko, Jamie ; Van Tubbergen, Christine ; Friedman, Cindy R. Less -
Description:
Extended-spectrum β-lactamases (ESBLs) confer resistance to clinically important third-generation cephalosporins, which are often used to treat invasive salmonellosis. In the United States, ESBLs are rarely found in Salmonella. However, in 2014, the US Food and Drug Administration found bla| ESBL-producing Salmonella enterica serotype Infantis in retail chicken meat. The isolate had a rare pulsed-field gel electrophoresis pattern. To clarify the sources and potential effects on human health, we examined isolates with this pattern obtained from human surveillance and associated metadata. Using broth microdilution for antimicrobial susceptibility testing and whole-genome sequencing, we characterized the isolates. Of 34 isolates, 29 carried the bla| gene with <9 additional resistance genes on 1 plasmid. Of 19 patients with travel information available, 12 (63%) reported recent travel to South America. Genetically, isolates from travelers, nontravelers, and retail chicken meat were similar. Expanded surveillance is needed to determine domestic sources and potentially prevent spread of this ESBL-containing plasmid.
Subject:
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Adolescent
Female
Humans
Immunization Programs
Papillomavirus Infections
Papillomavirus Vaccines
Uterine Cervical Neoplasms
Vaccination

Source:
Emerg Infect Dis. 24(12):2284-2291
Pubmed ID:
30457533
Pubmed Central ID:
PMC6256390
Document Type:
Journal Article
Name as Subject:
Centers for Disease Control and Prevention (U.S.)
Place as Subject:
United States
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:1aa21121f4cf34776e8d4a3270ccc7a5331a286eb5a37bfd106de1e6dc01b422
File Type:

Supporting Files

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