Chronic Exposure to Solvents Among Construction Painters: Reductions in Exposure and Neurobehavioral Health Effects

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Fiedler, Nancy ; Weisel, Clifford ; Nwankwo, Chizoba ; Kipen, Howard ; Lange, Gudrun ; Ohman-Strickland, Pamela ; Laumbach, Robert
• Description:
  Objective:
  
  To assess the neurobehavioral effects of lifetime solvent exposure by comparing the performance of painters and demographically comparable controls.
  
  Methods:
  
  Performance of exposed painters (N=133) was compared to unexposed tapers, glaziers, or carpenters (N=78) on the following domains: motor/perceptual speed, visual contrast, attention, working memory/planning, and visual and verbal memory. Lifetime exposure was estimated with questionnaires, field measurements, and paint composition.
  
  Results:
  
  After controlling for confounders, lifetime solvent exposure did not predict reduction in performance for overall domains of function. Lifetime solvent exposures predicted subtle alterations for individual tests of verbal learning, motor coordination, and visuospatial accuracy.
  
  Conclusions:
  
  Concentrations of solvents in paints have steadily declined during the working lifetime of subjects in this study. Although reduced performance was observed on individual tests, these alterations were not consistent across tests and unlikely to be of clinical significance.
  
  
• Subjects:
  Adult Article Attention Chronic Solvent Exposure Construction Industry Contrast Sensitivity Female Humans Male Memory, Short-Term Middle Aged Nervous System Diseases Neurobehavior Neuropsychological Tests Occupational Exposure Paint Painters Reaction Time Solvents

  More +
• Source:
  J Occup Environ Med. 60(12):e663-e670
• Pubmed ID:
  30308619
• Pubmed Central ID:
  PMC6289817
• Document Type:
  Journal Article
• Funding:
  P30 ES005022/ES/NIEHS NIH HHS/United States ; R01 OH008198/OH/NIOSH CDC HHS/United States
• Volume:
  60
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:ac5b43bd0a34ce11e56d2033dac18a4bee324c89aeb1f83a02a8347ca48c12c1
• Download URL:
  https://stacks.cdc.gov/view/cdc/61314/cdc_61314_DS1.pdf
• File Type:
  [PDF - 101.46 KB ]