Trends of racial and ethnic disparities in virologic suppression among women in the HIV Outpatient Study, USA, 2010-2015

Details

• Alternative Title:
  PLoS One
• Personal Author:
  Geter, Angelica ; Sutton, Madeline Y. ; Armon, Carl ; Durham, Marcus D. ; Palella, Frank J. ; Tedaldi, Ellen ; Hart, Rachel ; Buchacz, Kate
• Corporate Authors:
  on behalf of the HIV Outpatient Study Investigators
• Description:
  In the United States, women accounted for 19% of new HIV diagnoses in 2015 and were less likely to reach virologic suppression when compared to men. We assessed trends and disparities in virologic suppression among HIV-positive women to inform HIV treatment strategies. Data were from a prospective cohort of the HIV Outpatient Study and collected at nine United States HIV clinics. We included women aged ≥18 years, with ≥1 visit, who were prescribed antiretroviral therapy, and had ≥1 viral load test performed between 2010 and 2015. We defined virologic suppression as viral load <50 copies/mL and calculated adjusted prevalence ratios (aPR) with 95% confidence intervals (CI) for virologic suppression by race/ethnicity and year of measure. Generalized estimating equations were used for multivariable analyses to assess factors associated with virologic suppression. Among 809 women (median age = 44 years), 482 (60%) were black, 177 (22%) white, 150 (19%) Hispanic/Latina. Virologic suppression was less prevalent among black women (73%) compared with Hispanic/Latina women (83%) and white women (91%). In multivariable analyses, not achieving virologic suppression was more likely among black women (aPR = 2.13; CI = 1.50-3.02) or Hispanic/Latina women (aPR = 1.66; CI = 1.08-2.56) compared with white women, and among women who attended public clinics (aPR = 1.42; CI = 1.07-1.87) compared with those who attended a private clinic. Between 2010 and 2015, virologic suppression among HIV-positive women increased from 68% to 83%, but racial/ethnic disparities persisted. Black and Hispanic/Latina women had significantly lower rates of virologic suppression than white women. Interventions targeting virologic suppression improvement among HIV-positive women of color, especially those who attend public clinics, are warranted.
• Subjects:
  Adult Ethnicity Female HIV Infections Humans Middle Aged Outpatients Population Groups Prospective Studies Viral Load
• Source:
  PLoS One. 13(1).
• Pubmed ID:
  29293632
• Pubmed Central ID:
  PMC5749722
• Document Type:
  Journal Article
• Funding:
  U01 AI035039/AI/NIAID NIH HHS/United States
• Place as Subject:
  United States
• Volume:
  13
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:5d9975857cbf4b18322723b7942a9262c85db2cb0beec14d7ba86a1558b534a9
• Download URL:
  https://stacks.cdc.gov/view/cdc/61213/cdc_61213_DS1.pdf
• File Type:
  [PDF - 2.25 MB ]