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Evidence-Based Strategies for Preventing Opioid Overdose: What’s Working in the United States: An Introduction for Public Health, Law Enforcement, Local Organizations, and Others Striving to Serve their Community

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    This document is to assist community leaders, local and regional organizers, non-profit groups, law enforcement, public health, and members of the public in understanding and navigating effective strategies to prevent opioid overdose in their communities.

    Opioid use disorders and opioid overdose are complex phenomena shaped by numerous social, biological, and psychological factors. Due to this complexity— and the natural complexity of all human beings—fully understanding and accounting for all of these factors in an overdose prevention activity is a significant challenge. Often, ideas that once looked promising fail to pan out as expected.* There are also strategies that at first glance appeared counter-intuitive or wrong but were ultimately shown to be very effective in preventing fatal overdose. Subjecting overdose prevention interventions to scientific testing and evaluation is the only way to know for sure whether these intuitions are correct.

    In acknowledgement of this pressing need, a practice is considered both “locally appropriate” and “evidence-based” if it has been designed in accordance with three key sources of information: (1) high quality scientific research; (2) the professional opinions and experiences of clinical and public health experts; and (3) the preferences, priorities, and values of the individuals who will be targeted or affected by that practice.1 By offering this summary of the current “best practices” for overdose prevention, based on a thorough review of existing research and expertise from a diverse array of medical and public health professionals, this document aims to fulfill areas 1 (scientific research) and 2 (expert opinions). Area 3, the preferences and priorities of those affected (in this case, individuals who use opioids or are otherwise at risk of opioid overdose), must be sought anew in each new community context. This combination of evidence, expertise, and community dialog will lay the groundwork for truly effective opioid overdose prevention strategies across the U.S.

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    40 pdf pages
  • Citation:
    Suggested Citation: Centers for Disease Control and Prevention. Evidence-Based Strategies for Preventing Opioid Overdose: What’s Working in the United States. National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, U.S. Department of Health and Human Services, 2018.
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    urn:sha-512:32fa14a3fe4ae512fc4c11bc1fefd1ad1cc8d32a6a2a857df8a63be45fe04524dc7526acf211b075e313315b5982a86f551c0e53f0bafd10af8e3b0cfc50808b
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