Details:

Alternative Title:
Arch Phys Med Rehabil
Publisher's site:
http://dx.doi.org/10.1016/j.apmr.2016.02.009
Personal Author:
Chatelle, C ; Bodien, YG ; Carlowicz, C ; Wannez, S. ; Charland-Verville, V. ; ... More +
Chatelle, C ; Bodien, YG ; Carlowicz, C ; Wannez, S. ; Charland-Verville, V. ; Gosseries, O. ; Laureys, S ; Seel, RT ; Giacino, JT ; Less -
Description:
Objectives To determine the frequency with which specific Coma Recovery Scale-Revised (CRS-R) subscale scores co-occur as a means of providing clinicians and researchers with an empirical method of assessing CRS-R data quality. Design We retrospectively analyzed CRS-R subscale scores in hospital inpatients diagnosed with DoC to identify impossible and improbable subscore combinations as a means of detecting inaccurate and unusual scores. Impossible subscore combinations were based on violations of CRS-R scoring guidelines. To determine improbable subscore combinations, we relied on the Mahalanobis distance which detects outliers within a distribution of scores. Subscore pairs that were not observed at all in the database (i.e., frequency of occurrence = 0%) were also considered improbable. Setting Specialized DOC program and University hospital. Participants 1190 patients diagnosed with DoC (coma= 76, VS= 464, MCS= 586, EMCS= 64; 794 males; mean age= 43±20 years; traumatic etiology= 747; time post injury= 162±568 days). Interventions Not applicable. Main Outcome Measure(s) Impossible and improbable CRS-R subscore combinations. Results Of the 1190 CRS-R profiles analyzed, 4.7% were excluded because they met scoring criteria for impossible co-occurrence. Among the 1137 remaining profiles, 12.2% (41/336) of possible subscore combinations were classified as improbable. Conclusions Clinicians and researchers should take steps to ensure the accuracy of CRS-R scores. To minimize the risk of diagnostic error and erroneous research findings, we have identified 9 impossible and 36 improbable CRS-R subscore combinations. The presence of any one of these subscore combinations should trigger additional data quality review.
Subject:
[+]
Adult
Arousal
Article
Assessment
Brain Injuries
Communication
Consciousness Disorders
Data Quality
Disorders Of Consciousness
Female
Hearing Tests
Humans
Male
Middle Aged
Minimally Conscious State
Motor Activity
Physical Therapy Modalities
Recovery Of Function
Retrospective Studies
Trauma Severity Indices
Vegetative State
Vision Tests

Source:
Arch Phys Med Rehabil. 97(8):1295-1300.e4.
Pubmed ID:
26944708
Pubmed Central ID:
PMC6095641
Document Type:
Journal Article ;
Funding:
U48 DP000039/DP/NCCDPHP CDC HHS/United States ; UL1 TR001102/TR/NCATS NIH HHS/United States ;
U48 DP000039/DP/NCCDPHP CDC HHS/United States ; UL1 TR001102/TR/NCATS NIH HHS/United States ; Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:629f3e8552fffa44220d838ffe3db89095605068751b506a4412753b8606996c
File Type:

Supporting Files

• 	NIHMS983414-supplement-Supplemental.docx	docx
  	nihms983414.nxml	xml

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