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1995 revised guidelines for prophylaxis against pneumocystis carinii pneumonia for children infected with human immunodeficiency virus
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April 28, 1995
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Alternative Title:Revised guidelines for prophylaxis against pneumocystis carinii pneumonia for children infected with human immunodeficiency virus
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Description:"Pneumocystis carinii pneumonia (PCP) is the most common opportunistic infection in children who have acquired immunodeficiency syndrome (AIDS). Despite the publication of guidelines for prophylaxis against PCP for children infected with human immunodeficiency virus (HIV) in 1991 (1), ongoing AIDS surveillance has detected no substantial decrease in PCP incidence among HIV-infected infants. Studies indicate that this continued incidence is associated with failure to identify HIV-infected children before PCP occurs and with limitations in the ability of CD4+ measurements to identify children at risk for PCP. In March 1994, the National Pediatric & Family HIV Resource Center, in collaboration with CDC, convened a working group to review additional data about the occurrence of PCP among HIV-infected children and to reevaluate the 1991 PCP prophylaxis guidelines for children. This report summarizes these new data and presents revised PCP prevention guidelines that recommend a) promptly identifying children born to HIV-infected women and initiating regular diagnostic and immunologic monitoring of such children; b) beginning PCP prophylaxis at 4-6 weeks of age for all children who have been perinatally exposed to HIV; c) continuing prophylaxis through 12 months of age for HIV-infected children; and d) making decisions regarding prophylaxis for HIV-infected children > or = 12 months of age based on CD4+ measurements and whether PCP previously has occurred." - p. 1
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Content Notes:prepared by Samuel Grubman and James M. Oleski, National Pediatric & Family HIV Resource Center.
"The Working Group was supported in part by project # MCU-PRC021-02, Maternal and Child Health Bureau Program, Health Resources and Services Administration, U.S. Dept. of Health and Human Services."
"The material in this report was prepared for publication by: Samuel Grubman, James M. Oleske, National Pediatric & Family HIV Resource Center; in collaboration with: R.J. Simonds, Martha F. Rogers, Robin R. Moseley, Division of HIV/AIDS, National Center for Infectious Diseases, Centers for Disease Control and Prevention."
Includes bibliographical references (p. 10-11).
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