The eyes have it: influenza virus infection beyond the respiratory tract

Details

• Alternative Title:
  Lancet Infect Dis
• Personal Author:
  Belser, Jessica A ; Lash, R Ryan ; Garg, Shikha ; Tumpey, Terrence M ; Maines, Taronna R
• Description:
  Avian and human influenza A viruses alike have shown a capacity to use the eye as a portal of entry and cause ocular disease in human beings. However, whereas influenza viruses generally represent a respiratory pathogen and only occasionally cause ocular complications, the H7 virus subtype stands alone in possessing an ocular tropism. Clarifying what confers such non-respiratory tropism to a respiratory virus will permit a greater ability to identify, treat, and prevent zoonotic human infection following ocular exposure to influenza viruses; especially those within the H7 subtype, which continue to cause avian epidemics on many continents.
• Keywords:
  Communicable Diseases Conjunctivitis, Viral Humans Influenza, Human
• Source:
  Lancet Infect Dis. 18(7):e220-e227
• Pubmed ID:
  29477464
• Pubmed Central ID:
  PMC6035055
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  18
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:65f48c43bb16c30ecc5afc58bce7d278b8a71be661163ba501f840fee73837f1
• Download URL:
  https://stacks.cdc.gov/view/cdc/56759/cdc_56759_DS1.pdf
• File Type:
  [PDF - 464.60 KB ]