Addressing a Yellow Fever Vaccine Shortage — United States, 2016–2017

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Gershman, Mark D. ; Angelo, Kristina M. ; Ritchey, Julian ; Greenberg, David P. ; Muhammad, Riyadh D. ; Brunette, Gary ; Cetron, Martin S. ; Sotir, Mark J.
• Description:
  Recent manufacturing problems resulted in a shortage of the only U.S.-licensed yellow fever vaccine. This shortage is expected to lead to a complete depletion of yellow fever vaccine available for the immunization of U.S. travelers by mid-2017. CDC, the Food and Drug Administration (FDA), and Sanofi Pasteur are collaborating to ensure a continuous yellow fever vaccine supply in the United States. As part of this collaboration, Sanofi Pasteur submitted an expanded access investigational new drug (eIND) application to FDA in September 2016 to allow for the importation and use of an alternative yellow fever vaccine manufactured by Sanofi Pasteur France, with safety and efficacy comparable to the U.S.-licensed vaccine; the eIND was accepted by FDA in October 2016. The implementation of this eIND protocol included developing a systematic process for selecting a limited number of clinic sites to provide the vaccine. CDC and Sanofi Pasteur will continue to communicate with the public and other stakeholders, and CDC will provide a list of locations that will be administering the replacement vaccine at a later date.
• Subjects:
  Drug Approval Drugs, Investigational Full Report Humans Public Health Administration Travel Yellow Fever Yellow Fever Vaccine
• Source:
  MMWR Morbidity Mortal Weekly Rep. 66(17):457-459.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6617e2
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  28472025
• Pubmed Central ID:
  PMC5687078
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  3 pdf pages
• Volume:
  66
• Issue:
  17
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:e7a3dc32416a88b97c745772650d65e5af53eb136184c3192e5e4df2a3ca09e8919e4f699111a4cd0f01c25c73ececc9e78aa3d7d9678ee911a75f8a26b92fb8
• Download URL:
  https://stacks.cdc.gov/view/cdc/55788/cdc_55788_DS1.pdf
• File Type:
  [PDF - 76.67 KB ]