Interim Estimates of 2017–18 Seasonal Influenza Vaccine Effectiveness — United States, February 2018

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Flannery, Brendan ; Chung, Jessie R. ; Belongia, Edward A. ; McLean, Huong Q. ; Gaglani, Manjusha ; Murthy, Kempapura ; Zimmerman, Richard K. ; Nowalk, Mary Patricia ; Jackson, Michael L. ; Jackson, Lisa A. ; Monto, Arnold S. ; Martin, Emily T. ; Foust, Angie ; Sessions, Wendy ; Berman, LaShondra ; Barnes, John R. ; Spencer, Sarah ; Fry, Alicia M.
• Description:
  In the United States, annual vaccination against seasonal influenza is recommended for all persons aged ≥6 months (1). During each influenza season since 2004-05, CDC has estimated the effectiveness of seasonal influenza vaccine to prevent laboratory-confirmed influenza associated with medically attended acute respiratory illness (ARI). This report uses data from 4,562 children and adults enrolled in the U.S. Influenza Vaccine Effectiveness Network (U.S. Flu VE Network) during November 2, 2017-February 3, 2018. During this period, overall adjusted vaccine effectiveness (VE) against influenza A and influenza B Virus infection associated with medically attended ARI was 36% (95% confidence interval [CI] = 27%-44%). Most (69%) influenza infections were caused by A(H3N2) Viruses. VE was estimated to be 25% (CI = 13% to 36%) against illness caused by influenza A(H3N2) Virus, 67% (CI = 54%-76%) against A(H1N1)pdm09 Viruses, and 42% (CI = 25%-56%) against influenza B Viruses. These early VE estimates underscore the need for ongoing influenza Prevention and treatment measures. CDC continues to recommend influenza vaccination because the vaccine can still prevent some infections with currently circulating influenza Viruses, which are expected to continue circulating for several weeks. Even with current vaccine effectiveness estimates, vaccination will still prevent influenza illness, including thousands of hospitalizations and deaths. Persons aged ≥6 months who have not yet been vaccinated this season should be vaccinated.
• Subjects:
  Adolescent Adult Aged Child Child, Preschool Female Full Report Humans Infant Influenza, Human Influenza A Virus, H1N1 Subtype Influenza A Virus, H3N2 Subtype Influenza B Virus Influenza Vaccines Male Middle Aged Population Surveillance Seasons Young Adult

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• Source:
  MMWR Morbidity Mortal Weekly Rep. 67(6):180-185.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6706a2
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  29447141
• Pubmed Central ID:
  PMC5815489
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  6 pdf pages
• Volume:
  67
• Issue:
  6
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:ec0d2f70074631797757f098019869c605da38179c1b36f88509061c18a17812dc0937d3df2923c758c3fc33d1bf95d787ca1851730bab1fed3bf970af2a2ae1
• Download URL:
  https://stacks.cdc.gov/view/cdc/55114/cdc_55114_DS1.pdf
• File Type:
  [PDF - 248.42 KB ]