Pregnancy Outcomes After Maternal Zika Virus Infection During Pregnancy — U.S. Territories, January 1, 2016–April 25, 2017

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Shapiro-Mendoza, Carrie K. ; Rice, Marion E. ; Galang, Romeo R. ; Fulton, Anna C. ; VanMaldeghem, Kelley ; Prado, Miguel Valencia ; Ellis, Esther ; Anesi, Magele Scott ; Simeone, Regina M. ; Petersen, Emily E. ; Ellington, Sascha R. ; Jones, Abbey M. ; Williams, Tonya ; Reagan-Steiner, Sarah ; Perez-Padilla, Janice ; Deseda, Carmen C. ; Beron, Andrew ; Tufa, Aifili John ; Rosinger, Asher ; Roth, Nicole M. ; Green, Caitlin ; Martin, Stacey ; Lopez, Camille Delgado ; deWilde, Leah ; Goodwin, Mary ; Pagano, H. Pamela ; Mai, Cara T. ; Gould, Carolyn ; Zaki, Sherif ; Ferrer, Leishla Nieves ; Davis, Michelle S. ; Lathrop, Eva ; Polen, Kara ; Cragan, Janet D. ; Reynolds, Megan ; Newsome, Kimberly B. ; Huertas, Mariam Marcano ; Bhatangar, Julu ; Quiñones, Alma Martinez ; Nahabedian, John F. ; Adams, Laura ; Sharp, Tyler M. ; Hancock, W. Thane ; Rasmussen, Sonja A. ; Moore, Cynthia A. ; Jamieson, Denise J. ; Munoz-Jordan, Jorge L. ; Garstang, Helentina ; Kambui, Afeke ; Masao, Carolee ; Honein, Margaret A. ; Meaney-Delman, Dana ; Rico, Adriana ; Phippard, Alba ; Peterson, Alexis B. ; Pomales, Ana ; Arth, Annelise C. ; Dawson, April ; Rey, Araceli ; Figueroa, Argelia ; Sanchez, Audilis ; Robinson, Brittany ; Williams, Daniel B. ; Dee, Deborah L. ; Forbes, Divia P. ; Ailes, Elizabeth C. ; Marrero, Frances ; Fortenberry, Gamola Z. ; Razzaghi, Hilda ; Ko, Jean Y. ; Lind, Jennifer N. ; Dominguez, Kenneth Lee ; Clarke, Kristie ; Flores, Maria ; Biggerstaff, Matthew S. ; Danielson, Melissa ; Molina, Monica ; Somerville, Nicholas J. ; Blumenfeld, Rachel ; Tuff, Raegan A. ; Free, Rebecca J. ; Chae, Sae-Rom ; Andrist, Sara ; Kim, Shin Y. ; Williams, Tanya L. ; Harrington, Theresa A. ; Thomason, Tracy ; Krishnasamy, Vikram
• Corporate Authors:
  Zika Pregnancy and Infant Registries Working Group
• Description:
  Pregnant women living in or traveling to areas with local mosquito-borne Zika Virus Transmission are at risk for Zika Virus infection, which can lead to severe fetal and infant brain abnormalities and microcephaly (1). In February 2016, CDC recommended 1) routine tTesting for Zika Virus infection of asymptomatic pregnant women living in areas with ongoing local Zika Virus Transmission at the first prenatal care visit, 2) retTesting during the second trimester for women who initially test negative, and 3) tTesting of pregnant women with signs or symptoms consistent with Zika Virus disease (e.g., fever, rash, arthralgia, or conjunctivitis) at any time during pregnancy (2). To collect information about pregnant women with laboratory evidence of recent possible Zika Virus infection* and outcomes in their fetuses and infants, CDC established pregnancy and infant registries (3). During January 1, 2016-April 25, 2017, U.S. territories| with local Transmission of Zika Virus reported 2,549 completed pregnancies| (live births and pregnancy losses at any gestational age) with laboratory evidence of recent possible Zika Virus infection; 5% of fetuses or infants resulting from these pregnancies had birth defects potentially associated with Zika Virus infection| (4,5). Among completed pregnancies with positive nucleic acid tests confirming Zika infection identified in the first, second, and third trimesters, the percentage of fetuses or infants with possible Zika-associated birth defects was 8%, 5%, and 4%, respectively. Among liveborn infants, 59% had Zika laboratory tTesting results reported to the pregnancy and infant registries. Identification and follow-up of infants born to women with laboratory evidence of recent possible Zika Virus infection during pregnancy permits timely and appropriate clinical intervention services (6).
• Subjects:
  Female Full Report Humans Infant, Newborn Pregnancy Pregnancy Complications, Infectious Pregnancy Outcome Zika Virus Infection
• Source:
  MMWR Morbidity Mortal Weekly Rep. 66(23):615-621.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6623e1
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  28617773
• Pubmed Central ID:
  PMC5657842
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  7 pdf pages
• Volume:
  66
• Issue:
  23
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:d55c93f2a89b6e2c8b34004aad793678aadf4ef80bf20a128238d58625b5df4114d6b44c177508fe580bb76dd7bd7c7799b4af3c64e9e6e9c95d1ffec6619af6
• Download URL:
  https://stacks.cdc.gov/view/cdc/54525/cdc_54525_DS1.pdf
• File Type:
  [PDF - 114.96 KB ]