Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Publisher's site:
http://dx.doi.org/10.15585/mmwr.mm6619a5
Personal Author:
Abara, Winston E. ; Cha, Susan ; Malik, Tasneem ; DeSimone, Mia S. ; Schumann, Bernadette ; ... More +
Abara, Winston E. ; Cha, Susan ; Malik, Tasneem ; DeSimone, Mia S. ; Schumann, Bernadette ; Mallada, Esther ; Klemme, Michael ; Aguon, Vince ; Santos, Anne Marie ; Collier, Melissa ; Kamb, Mary Less -
Corporate Authors:
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.)Division of Sexually Transmitted Diseases Prevention. ; National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.)Division of Viral Hepatitis. ; Centers for Dsease Control and Prevention (U.S.)Epidemic Intelligence Service.
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.)Division of Sexually Transmitted Diseases Prevention. ; National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (U.S.)Division of Viral Hepatitis. ; Centers for Dsease Control and Prevention (U.S.)Epidemic Intelligence Service. Less -
Description:
Hepatitis B Virus (HBV) infection is endemic among adults in the U.S. territory of Guam (1,2). Perinatal HBV Transmission, which occurs at birth from an infected mother to her newborn infant, is a major mode of HBV Transmission and maintains HBV endemicity (3). Approximately 90% of HBV-infected infants will develop chronic HBV infection, and approximately 25% of those will die prematurely from liver failure or hepatocellular carcinoma (4,5). Since 1988, the Advisory Committee on Immunization Practices has recommended that all pregnant women be screened for hepatitis B surface antigen (HBsAg), an indicator of HBV infection, and that infants of women who screen positive (HBsAg-positive women) receive postexposure prophylaxis (PEP) (hepatitis B vaccine and hepatitis B immunoglobulin [HBIG]). When received within 12 hours of birth, PEP is 85%-95% effective in preventing perinatal HBV Transmission (5,6). Hepatitis B vaccine provides long-term active immunity to HBV infection and HBIG provides short-term passive immunity to HBV infection until the infant responds to the vaccine (5). Hepatitis B vaccine was introduced into the routine universal infant vaccination schedule in Guam in 1988 (1).
Subjects:
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Adolescent Adult Female Full Report Guam Hepatitis B Hepatitis B Surface Antigens Hepatitis B Vaccines Humans Immunization Schedule Immunoglobulins Infant Infectious Disease Transmission, Vertical Mass Screening Maternal-Child Health Services Middle Aged Post-Exposure Prophylaxis Pregnancy Pregnancy Complications, Infectious Young Adult
Source:
MMWR Morb Mortal Wkly Rep. 66(19):506-508.
Pubmed ID:
28520708
Pubmed Central ID:
PMC5657642
Document Type:
Journal Article
Place as Subject:
Guam
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:67a2a85d30cd3facc891477237495c8204ff158690d78d12160454973eda39fb
Download URL:
https://stacks.cdc.gov/view/cdc/54493/cdc_54493_DS1.pdf
File Type:

Supporting Files

• mm6619a5.nxml

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