Morbidity and Mortality Weekly Report: Recommendations and Reports, October 16, 2009 / Vol. 58 / No. RR-12

Details

• Alternative Title:
  Recommendations for Diagnosis of Shiga Toxin-Producing Escherichia coli Infections by Clinical Laboratories
• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports
• Personal Author:
  Gould, L. Hannah ; Bopp, Cheryl ; Strockbine, Nancy ; Atkinson, Robyn ; Baselski, Vickie ; Body, Barbara ; Carey, Roberta ; Crandall, Claudia ; Hurd, Sharon ; Kaplan, Ray ; Neill, Marguerite ; Shea, Shari ; Somsel, Patricia ; Tobin-D’Angelo, Melissa ; Griffin, Patricia M. ; Gerner-Smid, Peter
• Corporate Authors:
  National Center for Zoonotic, Vector-Borne, and Enteric Diseases (U.S.). Division of Foodborne, Bacterial, and Mycotic Diseases.
• Description:
  "Shiga toxin--producing Escherichia coli (STEC) are a leading cause of bacterial enteric infections in the United States. Prompt, accurate diagnosis of STEC infection is important because appropriate treatment early in the course of infection might decrease the risk for serious complications such as renal damage and improve overall patient outcome. In addition, prompt laboratory identification of STEC strains is essential for detecting new and emerging serotypes, for effective and timely outbreak responses and control measures, and for monitoring trends in disease epidemiology. Guidelines for laboratory identification of STEC infections by clinical laboratories were published in 2006 (1). This report provides comprehensive and detailed recommendations for STEC testing by clinical laboratories, including the recommendation that all stools submitted for routine testing from patients with acute community-acquired diarrhea (regardless of patient age, season of the year, or presence or absence of blood in the stool) be simultaneously cultured for E. coli O157:H7 (O157 STEC) and tested with an assay that detects Shiga toxins to detect non-O157 STEC. The report also includes detailed procedures for specimen selection, handling, and transport; a review of culture and nonculture tests for STEC detection; and clinical considerations and recommendations for management of patients with STEC infection. Improving the diagnostic accuracy of STEC infection by clinical laboratories should ensure prompt diagnosis and treatment of these infections in patients and increase detection of STEC outbreaks in the community." - p. 1
• Content Notes:
  Includes bibliographical references (p. 12-14).
• Subjects:
  Bacteriological Techniques Disease Outbreaks Escherichia Coli Infections / Diagnosis Escherichia Coli Infections / Epidemiology Escherichia Coli O157 / Genetics Escherichia Coli O157 / Isolation & Purification Escherichia Coli O157 / Pathogenicity Feces / Microbiology Food Contamination Hemolytic-Uremic Syndrome / Microbiology Humans Immunoassay / Methods Laboratories Polymerase Chain Reaction Shiga-Toxigenic Escherichia Coli / Genetics Shiga-Toxigenic Escherichia Coli / Isolation & Purification* Shiga-Toxigenic Escherichia Coli / Pathogenicity Shiga Toxins / Analysis Shiga Toxins / Genetics Specimen Handling United States / Epidemiology

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• Source:
  Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, 2009; v. 58, no. 12
• Series:
  Recommendations and Reports: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  1057-5987 (print) ; 1545-8601 (digital)
• Pubmed ID:
  19834454
• Document Type:
  Journal Issue
• Genre:
  Guideline
• Place as Subject:
  United States
• Pages in Document:
  20 pdf pages
• Volume:
  58
• Issue:
  12
• Collection(s):
  Guidelines and Recommendations Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:956f3b50782eea5c440e257fe44abb8579944341a20626561190d044bc43a5b79c8bc08b7f6c1376b7a82bad2e03f8116009ed35651026f9e8f0969a0d14ecce
• Download URL:
  https://stacks.cdc.gov/view/cdc/5437/cdc_5437_DS1.pdf
• File Type:
  [PDF - 286.15 KB ]