Morbidity and Mortality Weekly Report: Recommendations and Reports, October 16, 2009 / Vol. 58 / No. RR-12
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Public Domain
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October 16, 2009
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Status Current
File Language:
English
Details
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Alternative Title:Recommendations for Diagnosis of Shiga Toxin-Producing Escherichia coli Infections by Clinical Laboratories
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Journal Article:Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports
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Personal Author:Gould, L. Hannah ; Bopp, Cheryl ; Strockbine, Nancy ; Atkinson, Robyn ; Baselski, Vickie ; Body, Barbara ; Carey, Roberta ; Crandall, Claudia ; Hurd, Sharon ; Kaplan, Ray ; Neill, Marguerite ; Shea, Shari ; Somsel, Patricia ; Tobin-D’Angelo, Melissa ; Griffin, Patricia M. ; Gerner-Smid, Peter
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Corporate Authors:
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Description:"Shiga toxin--producing Escherichia coli (STEC) are a leading cause of bacterial enteric infections in the United States. Prompt, accurate diagnosis of STEC infection is important because appropriate treatment early in the course of infection might decrease the risk for serious complications such as renal damage and improve overall patient outcome. In addition, prompt laboratory identification of STEC strains is essential for detecting new and emerging serotypes, for effective and timely outbreak responses and control measures, and for monitoring trends in disease epidemiology. Guidelines for laboratory identification of STEC infections by clinical laboratories were published in 2006 (1). This report provides comprehensive and detailed recommendations for STEC testing by clinical laboratories, including the recommendation that all stools submitted for routine testing from patients with acute community-acquired diarrhea (regardless of patient age, season of the year, or presence or absence of blood in the stool) be simultaneously cultured for E. coli O157:H7 (O157 STEC) and tested with an assay that detects Shiga toxins to detect non-O157 STEC. The report also includes detailed procedures for specimen selection, handling, and transport; a review of culture and nonculture tests for STEC detection; and clinical considerations and recommendations for management of patients with STEC infection. Improving the diagnostic accuracy of STEC infection by clinical laboratories should ensure prompt diagnosis and treatment of these infections in patients and increase detection of STEC outbreaks in the community." - p. 1
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Content Notes:Includes bibliographical references (p. 12-14).
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Subjects:
- Bacteriological Techniques
- Disease Outbreaks
- Escherichia coli Infections / diagnosis
- Escherichia coli Infections / epidemiology
- Escherichia coli O157 / genetics
- Escherichia coli O157 / isolation & purification
- Escherichia coli O157 / pathogenicity
- Feces / microbiology
- Food Contamination
- Hemolytic-Uremic Syndrome / microbiology
- Humans
- Immunoassay / methods
- Laboratories
- Polymerase Chain Reaction
- Shiga Toxins / analysis
- Shiga Toxins / genetics
- Shiga-Toxigenic Escherichia coli / genetics
- Shiga-Toxigenic Escherichia coli / isolation & purification*
- Shiga-Toxigenic Escherichia coli / pathogenicity
- Specimen Handling
- United States / epidemiology
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Source:Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, 2009; v. 58, no. 12
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Series:
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ISSN:1057-5987 (print) ; 1545-8601 (digital)
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Pubmed ID:19834454
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Document Type:
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Genre:
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Place as Subject:
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Pages in Document:20 pdf pages
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Volume:58
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Issue:12
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Download URL:
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File Type:
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Collection(s):
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Main Document Checksum:urn:sha-512:956f3b50782eea5c440e257fe44abb8579944341a20626561190d044bc43a5b79c8bc08b7f6c1376b7a82bad2e03f8116009ed35651026f9e8f0969a0d14ecce
File Language:
English
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