Implementation of Rotavirus Surveillance and Vaccine Introduction — World Health Organization African Region, 2007–2016

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Mwenda, Jason M. ; Burke, Rachel M. ; Shaba, Keith ; Mihigo, Richard ; Tevi-Benissan, Mable Carole ; Mumba, Mutale ; Biey, Joseph Nsiari-Muzeyi ; Cheikh, Dah ; Poy, MSc, Alain ; Zawaira, Felicitas R. ; Aliabadi, Negar ; Tate, Jacqueline E. ; Hyde, Terri ; Cohen, Adam L. ; Parashar, Umesh D.
  More +
• Corporate Authors:
  World Health Organization.
• Description:
  RotaVirus is a leading cause of severe pediatric diarrhea globally, estimated to have caused 120,000 deaths among children aged <5 years in sub-Saharan Africa in 2013 (1). In 2009, the World Health Organization (WHO) recommended rotaVirus vaccination for all infants Worldwide (2). Two rotaVirus vaccines are currently licensed globally: the monovalent Rotarix vaccine (RV1, GlaxoSmithKline; 2-dose series) and the pentavalent RotaTeq vaccine (RV5, Merck; 3-dose series). This report describes progress of rotaVirus vaccine introduction (3), coverage (using estimates from WHO and the United Nations Children's Fund UNICEF) (4), and impact on pediatric diarrhea hospitalizations in the WHO African Region. By December 2016, 31 (66%) of 47 countries in the WHO African Region had introduced rotaVirus vaccine, including 26 that introduced RV1 and five that introduced RV5. Among these countries, rotaVirus vaccination coverage (completed series) was 77%, according to WHO/UNICEF population-weighted estimates. In 12 countries with Surveillance data available before and after vaccine introduction, the proportion of pediatric diarrhea hospitalizations that were rotaVirus-positive declined 33%, from 39% preintroduction to 26% following rotaVirus vaccine introduction. These results support introduction of rotaVirus vaccine in the remaining countries in the region and continuation of rotaVirus Surveillance to monitor impact.
• Subjects:
  • Full Report
  • Child, Preschool
  • Feces
  • Humans
  • Immunization Programs
  • Immunization Schedule
  • Infant
  • Population Surveillance
  • RotaVirus
  • RotaVirus Infections
  More +
• Source:
  MMWR Morbidity Mortal Weekly Rep. 66(43):1192-1196.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6643a7
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  29095805
• Pubmed Central ID:
  PMC5689217
• Document Type:
  Journal Article
• Place as Subject:
  Africa
• Pages in Document:
  5 pdf pages
• Volume:
  66
• Issue:
  43
• Download URL:
  https://stacks.cdc.gov/view/cdc/54270/cdc_54270_DS1.pdf
• File Type:
  [PDF - 504.16 KB]
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:b9991c9f57e02a7529f6680421474e988a4baf840440b1998fa62bb3dda4c88846633bcd2b3fcc9ee70cee778f00b3e725d81951aed97a7daf2b85eb7bfc4a5b