Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Mwenda, Jason M. ; Burke, Rachel M. ; Shaba, Keith ; Mihigo, Richard ; Tevi-Benissan, Mable Carole ; ... More +
Mwenda, Jason M. ; Burke, Rachel M. ; Shaba, Keith ; Mihigo, Richard ; Tevi-Benissan, Mable Carole ; Mumba, Mutale ; Biey, Joseph Nsiari-Muzeyi ; Cheikh, Dah ; Poy, MSc, Alain ; Zawaira, Felicitas R. ; Aliabadi, Negar ; Tate, Jacqueline E. ; Hyde, Terri ; Cohen, Adam L. ; Parashar, Umesh D. Less -
Corporate Authors:
World Health Organization.
Description:
RotaVirus is a leading cause of severe pediatric diarrhea globally, estimated to have caused 120,000 deaths among children aged <5 years in sub-Saharan Africa in 2013 (1). In 2009, the World Health Organization (WHO) recommended rotaVirus vaccination for all infants Worldwide (2). Two rotaVirus vaccines are currently licensed globally: the monovalent Rotarix vaccine (RV1, GlaxoSmithKline; 2-dose series) and the pentavalent RotaTeq vaccine (RV5, Merck; 3-dose series). This report describes progress of rotaVirus vaccine introduction (3), coverage (using estimates from WHO and the United Nations Children's Fund [UNICEF]) (4), and impact on pediatric diarrhea hospitalizations in the WHO African Region. By December 2016, 31 (66%) of 47 countries in the WHO African Region had introduced rotaVirus vaccine, including 26 that introduced RV1 and five that introduced RV5. Among these countries, rotaVirus vaccination coverage (completed series) was 77%, according to WHO/UNICEF population-weighted estimates. In 12 countries with Surveillance data available before and after vaccine introduction, the proportion of pediatric diarrhea hospitalizations that were rotaVirus-positive declined 33%, from 39% preintroduction to 26% following rotaVirus vaccine introduction. These results support introduction of rotaVirus vaccine in the remaining countries in the region and continuation of rotaVirus Surveillance to monitor impact.
Subjects:
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Child, Preschool Feces Full Report Humans Immunization Programs Immunization Schedule Infant Population Surveillance RotaVirus RotaVirus Infections RotaVirus Vaccines
Source:
MMWR Morb Mortal Wkly Rep. 66(43):1192-1196.
Pubmed ID:
29095805
Pubmed Central ID:
PMC5689217
Document Type:
Journal Article
Place as Subject:
Africa
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:cf84232cce29a9e65d06b9e45eab4be44b2743eaa99c0ec172289b417c183ef9
Download URL:
https://stacks.cdc.gov/view/cdc/54270/cdc_54270_DS1.pdf
File Type:

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