Outbreak of Seoul Virus Among Rats and Rat Owners — United States and Canada, 2017

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Kerins, Janna L. ; Koske, Sarah E. ; Kazmierczak, James ; Austin, Connie ; Gowdy, Karen ; Dibernardo, Antonia ; Achenbach, Jan ; Baber, Jill ; Balsamo, Gary ; Behravesh, Casey Barton ; Blythe, David ; Boraks-Pielechaty, Iwona ; Brown, Shelley M. ; Brown, Jennifer ; Brucker, Robert ; Bruen, Barbara A. ; Campbell, Colin ; Cannon, Deborah ; Carlson, Beth ; Carter, Kris ; Cary, Cynthia ; Castillo, Caroline ; Chiang, Cheng-Feng ; Choi, Mary ; Christel, Ellen ; Clayton, April ; Colton, Leah ; Cronquist, Laura ; Damsker, David ; Davis, William G. ; de St Maurice, Annabelle ; Dieckman, Jordan ; Dunn, John ; Dycus, Drew D. ; Ervin, Elizabeth ; Feist, Michelle ; Feldpausch, Amanda ; Fill, Mary Margaret ; Gabel, Julie ; Garvey, Ann ; Genzer, Sarah ; Gibbons-Burgener, Suzanne ; Graziano, James ; Hall, Victoria ; Heisey, Russel ; Henderson, Heather ; Hennebelle, Janemarie ; Hiber, Leslie ; Holzbauer, Stacy ; House, Jennifer ; Jackson, Eddie ; Jenks, Mary H. ; CDC, Dee Jones ; Keller, Susan ; Klena, John D. ; Klos, Rachel F. ; Knust, Barbara ; Kocharian, Anna ; Kohl, Katrin ; Langham, Gregory ; Lathrop, George ; Layden, Jennifer ; Lehatto, Kathryn ; Lovejoy, Jodi ; Lowery, Kenneth ; Lukovsky-Akhsanov, Nicole ; Luong, Nhiem ; Maglio, Michael ; Manning, Craig ; Marriott, Chandra ; Marzec, Natalie ; Masters, Michel ; McClanahan, Susan ; McCloskey, Lisa ; McKnight, Shannon ; McQuiston, Jennifer ; McReynolds, Sara ; Megaro, Gianna ; Morales-Betoulle, Maria ; Nakashima, Allyn K. ; Nichol, Stuart ; Paoline, Julie ; Patel, Nishi ; Patel, Ketan ; Peterson, Dallin ; Posivak-Khouly, Leah ; Powell, Nathaniel ; Pue, Howard ; Purpura, Lawrence ; Radcliffe, Rachel ; Reynolds, Nicole ; Roesch, Linda ; Rollin, Pierre ; Sandberg, Andrea L. ; Scheftel, Joni ; Schroeder, Betsy ; Shaikh, Irshad A. ; Shoemaker, Trevor ; Sidge, Jennifer ; Sidwa, Tom ; Signs, Kim ; Singh, Amber ; Smee, Aaron ; Stanek, Danielle ; Stobierski, Mary Grace ; Straily, Anne ; Ströher, Ute ; Tansey, Cassandra ; Tengelsen, Leslie ; Thompson, Beth ; Ward, Susan L. ; Warren, Kimberly ; Weinstein, Susan ; Weiss, Deborah ; Weltman, Andre ; Yirko, Tigist ; Zuzack, Joyce ; Buck, Peter A. ; Grolla, Allen ; Huynh, Chris ; Lindsay, L. Robbin ; Loomer, Courtney ; Safronetz, David ; Sloan, Angela ; Strong, Jim E. ; Tataryn, Joanne R. ; Vrbova, Linda
• Corporate Authors:
  Seoul Virus Working Group ; Canadian Seoul Virus Investigation Group (Federal) ; Canadian Seoul Virus Investigation Group (Provincial) ; Contributors
• Description:
  In December 2016, the Wisconsin Department of Health Services (WDHS) notified CDC of a patient hospitalized with fever, leukopenia, elevated transaminases, and proteinuria. The patient owned and operated an in-home rattery, or rat-breeding facility, with approximately 100 Norway rats, primarily bred as pets. A family member developed similar symptoms 4 weeks later, but was not hospitalized. Because both patients were known to have rodent contact, they were tested for hantavirus infections. In January 2017, CDC confirmed recent, acute Seoul virus infection in both patients. An investigation was conducted to identify additional human and rat infections and prevent further transmission. Ultimately, the investigation identified 31 facilities in 11 states with human and/or rat Seoul virus infections; six facilities also reported exchanging rats with Canadian ratteries. Testing of serum samples from 183 persons in the United States and Canada identified 24 (13.1%) with Seoul virus antibodies; three (12.5%) were hospitalized and no deaths occurred. This investigation, including cases described in a previously published report from Tennessee (1), identified the first known transmission of Seoul virus from pet rats to humans in the United States and Canada. Pet rat owners should practice safe rodent handling to prevent Seoul virus infection (2).
• Subjects:
  Animals Disease Outbreaks Full Report Hemorrhagic Fever With Renal Syndrome Humans Ownership Rats Rodent Diseases Seoul Virus
• Source:
  MMWR Morbidity Mortal Weekly Rep. 67(4):131-134.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6704a5
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  29393924
• Pubmed Central ID:
  PMC5794350
• Document Type:
  Journal Article
• Place as Subject:
  Canada ; United States
• Pages in Document:
  4 pdf pages
• Volume:
  67
• Issue:
  4
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:dede8b07fdc14d0f1c4774266a2f080a97fff09543f6f7829dab748ea6568135e68f8e8d355fee52acafbb9935b1b6c09955baf79e4c0884f6403d13e36d402a
• Download URL:
  https://stacks.cdc.gov/view/cdc/53924/cdc_53924_DS1.pdf
• File Type:
  [PDF - 80.48 KB ]