Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak — Liberia, 2017

Patel, Jaymin C.; George, Josiah; Vuong, Jeni; Potts, Caelin C.; Bozio, Catherine H.; Clark, Thomas A.; Thomas, Jerry; Schier, Joshua; Chang, Arthur; Waller, Jessica L.; Diaz, Maureen H.; Whaley, Melissa; Jenkins, Laurel T.; Fuller, Serena; Williams, Desmond E.; Redd, John T.; Arthur, Ray R.; Taweh, Fahn; Vera Walker, Yatta; Hardy, Patrick; Freeman, Maxwell; Katawera, Victoria; Gwesa, Gulu; Gbanya, Miatta Z.; Clement, Peter; Kohar, Henry; Stone, Mardia; Fallah, Mosoka; Nyenswah, Tolbert; Winchell, Jonas M.; Wang, Xin; McNamara, Lucy A.; Dokubo, E. Kainne; Fox, LeAnne M.

doi:10.15585/mmwr.mm6642a5

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Rapid Laboratory Identification of Neisseria meningitidis Serogroup C as the Cause of an Outbreak — Liberia, 2017

Published Date:

Oct 27 2017

Publisher's site:

http://dx.doi.org/10.15585/mmwr.mm6642a5 New Site Icon

Source:

MMWR Morb Mortal Wkly Rep. 66(42):1144-1147.

Language:

English

[PDF-187.07 KB]

Details:

Personal Authors:

Patel, Jaymin C. ; George, Josiah ; Vuong, Jeni ; Potts, Caelin C. ; Bozio, Catherine H. ; ... More ▼

Keywords:

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Pubmed ID:

29073124

Pubmed Central ID:

PMC5689101

Description:

On April 25, 2017, a cluster of unexplained illness and deaths among persons who had attended a funeral during April 21-22 was reported in Sinoe County, Liberia (1). Using a broad initial case definition, 31 cases were identified, including 13 (42%) deaths. Twenty-seven cases were from Sinoe County (1), and two cases each were from Grand Bassa and Monsterrado counties, respectively. On May 5, 2017, initial multipathogen testing of specimens from four fatal cases using the Taqman Array Card (TAC) assay identified Neisseria meningitidis in all specimens. Subsequent testing using direct real-time polymerase chain reaction (PCR) confirmed N. meningitidis in 14 (58%) of 24 patients with available specimens and identified N. meningitidis serogroup C (NmC) in 13 (54%) patients. N. meningitidis was detected in specimens from 11 of the 13 patients who died; no specimens were available from the other two fatal cases. On May 16, 2017, the National Public Health Institute of Liberia and the Ministry of Health of Liberia issued a press release confirming serogroup C meningococcal disease as the cause of this outbreak in Liberia.

Document Type:

Journal Article

Collection(s):

Morbidity and Mortality Weekly Report (MMWR)

Main Document Checksum:

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Supporting Files:

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