Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Publisher's site:
http://dx.doi.org/10.15585/mmwr.mm6642a5
Personal Author:
Patel, Jaymin C. ; George, Josiah ; Vuong, Jeni ; Potts, Caelin C. ; Bozio, Catherine H. ; ... More +
Patel, Jaymin C. ; George, Josiah ; Vuong, Jeni ; Potts, Caelin C. ; Bozio, Catherine H. ; Clark, Thomas A. ; Thomas, Jerry ; Schier, Joshua ; Chang, Arthur ; Waller, Jessica L. ; Diaz, Maureen H. ; Whaley, Melissa ; Jenkins, Laurel T. ; Fuller, Serena ; Williams, Desmond E. ; Redd, John T. ; Arthur, Ray R. ; Taweh, Fahn ; Vera Walker, Yatta ; Hardy, Patrick ; Freeman, Maxwell ; Katawera, Victoria ; Gwesa, Gulu ; Gbanya, Miatta Z. ; Clement, Peter ; Kohar, Henry ; Stone, Mardia ; Fallah, Mosoka ; Nyenswah, Tolbert ; Winchell, Jonas M. ; Wang, Xin ; McNamara, Lucy A. ; Dokubo, E. Kainne ; Fox, LeAnne M. ; Less -
Description:
On April 25, 2017, a cluster of unexplained illness and deaths among persons who had attended a funeral during April 21-22 was reported in Sinoe County, Liberia (1). Using a broad initial case definition, 31 cases were identified, including 13 (42%) deaths. Twenty-seven cases were from Sinoe County (1), and two cases each were from Grand Bassa and Monsterrado counties, respectively. On May 5, 2017, initial multipathogen testing of specimens from four fatal cases using the Taqman Array Card (TAC) assay identified Neisseria meningitidis in all specimens. Subsequent testing using direct real-time polymerase chain reaction (PCR) confirmed N. meningitidis in 14 (58%) of 24 patients with available specimens and identified N. meningitidis serogroup C (NmC) in 13 (54%) patients. N. meningitidis was detected in specimens from 11 of the 13 patients who died; no specimens were available from the other two fatal cases. On May 16, 2017, the National Public Health Institute of Liberia and the Ministry of Health of Liberia issued a press release confirming serogroup C meningococcal disease as the cause of this outbreak in Liberia.
Subject:
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Clinical Laboratory Services
Cluster Analysis
Disease Outbreaks
Full Report
Humans
Liberia
Meningitis, Meningococcal
Neisseria Meningitidis, Serogroup C
Real-Time Polymerase Chain Reaction
Time Factors

Source:
MMWR Morb Mortal Wkly Rep. 66(42):1144-1147.
Pubmed ID:
29073124
Pubmed Central ID:
PMC5689101
Document Type:
Journal Article ;
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:7e90c80a473fc97cf1ecd337d0d30c6dfeb02ffe61bebbea2d7597c1f2c185c2
File Type:

Supporting Files

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  	mm6642a5.nxml	xml

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