A critical appraisal of the mild axonal peripheral neuropathy of late neurologic Lyme disease

Details

• Alternative Title:
  Diagn Microbiol Infect Dis
• Personal Author:
  Wormser, Gary P. ; Strle, Franc ; Shapiro, Eugene D. ; Dattwyler, Raymond J. ; Auwaerter, Paul G.
• Description:
  In older studies, a chronic distal symmetric sensory neuropathy was reported as a relatively common manifestation of late Lyme disease in the United States. However, the original papers describing this entity had notable inconsistencies and certain inexplicable findings, such as reports that this condition developed in patients despite prior antibiotic treatment known to be highly effective for other manifestations of Lyme disease. More recent literature suggests that this entity is seen rarely, if at all. A chronic distal symmetric sensory neuropathy as a manifestation of late Lyme disease in North America should be regarded as controversial and in need of rigorous validation studies before acceptance as a documented clinical entity.
• Subjects:
  Humans Lyme Neuroborreliosis Peripheral Nervous System Diseases
• Source:
  Diagn Microbiol Infect Dis. 87(2):163-167.
• Pubmed ID:
  27914746
• Pubmed Central ID:
  PMC5924701
• Document Type:
  Journal Article
• Funding:
  R01 CK000152/CK/NCEZID CDC HHS/United States ; KL2 TR000140/TR/NCATS NIH HHS/United States ; UL1 TR000142/TR/NCATS NIH HHS/United States ; R43 AI122399/AI/NIAID NIH HHS/United States ; KL2 TR001862/TR/NCATS NIH HHS/United States ; R43 AI120364/AI/NIAID NIH HHS/United States ; R44 AI102435/AI/NIAID NIH HHS/United States
• Place as Subject:
  Americas ; North America
• Volume:
  87
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:a316c524abf3110d5d44651d24b67a7e362164346c0e9282c579f101f43a467f
• Download URL:
  https://stacks.cdc.gov/view/cdc/53774/cdc_53774_DS1.pdf
• File Type:
  [PDF - 72.61 KB ]