Epidemiology and Molecular Characteristics of Norovirus GII.4 Sydney Outbreaks in Taiwan, January 2012–December 2013

Wu, Fang-Tzy; Chen, Hsieh-Cheng; Yen, Catherine; Wu, Ching-Yi; Katayama, Kazuhiko; Park, YoungBin; Hall, Aron J.; Vinjé, Jan; Huang, Jason C.; Wu, Ho-Sheng

doi:10.1002/jmv.24208

i

Epidemiology and Molecular Characteristics of Norovirus GII.4 Sydney Outbreaks in Taiwan, January 2012–December 2013

Supporting Files

9 2015
By Wu, Fang-Tzy ; Chen, Hsieh-Cheng ; Yen, Catherine ; ...

File Language:

English

Details

Alternative Title:

J Med Virol
Personal Author:

Wu, Fang-Tzy ; Chen, Hsieh-Cheng ; Yen, Catherine ; Wu, Ching-Yi ; Katayama, Kazuhiko ; Park, YoungBin ; Hall, Aron J. ; Vinjé, Jan ; Huang, Jason C. ; Wu, Ho-Sheng
Description:

In 2012, a new norovirus GII.4 variant (GII.4 Sydney) emerged and caused the majority of the acute gastroenteritis outbreaks in Australia, Asia, Europe, and North America. We examined the epidemiologic and molecular virologic characteristics of reported acute gastroenteritis outbreaks determined to be caused by norovirus in Taiwan from January 2012 to December 2013. A total of 253 (45.7%) of 552 reported acute gastroenteritis outbreaks tested positive for norovirus, of which 165 (65.5%) were typed as GII.4 Sydney. GII.4 Sydney outbreaks were reported from all geographic areas of Taiwan and occurred most frequently in schools (35.8%) and long-term care facilities (24.2%). Person-to-person transmission was identified in 116 (70.3%) of the outbreaks. Phylogenetic analyses of full-length ORF2 of eight specimens indicated that GII.4 Sydney strains detected in Taiwan were closely related to strains detected globally. Continued outbreak surveillance and strain typing are needed to provide information on epidemiologic and virologic trends of novel norovirus strains.
Subjects:

Caliciviridae Infections Disease Outbreaks Feces Gastroenteritis Genotype Humans Norovirus Phylogeny Sequence Analysis, DNA Taiwan Time Factors
Keywords:

Epidemiology Norovirus GII.4 Sydney Outbreak Phylogenetic Analysis
Source:

J Med Virol. 87(9):1462-1470
Pubmed ID:

25946552
Pubmed Central ID:

PMC5911914
Document Type:

Journal Article
Funding:

CC999999/Intramural CDC HHSUnited States/
Volume:

87
Issue:

9
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:7b46f52dd2b38ee29c2d7812cb28fc16730645baab70514dfd34d0d347968972
Download URL:

https://stacks.cdc.gov/view/cdc/53622/cdc_53622_DS1.pdf
File Type:

[PDF - 1.63 MB ]

File Language:

English

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