Prevalence of Amyotrophic Lateral Sclerosis — United States, 2014

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Personal Author:
  Mehta, Paul ; Kaye, Wendy ; Raymond, Jaime ; Wu, Ruoming ; Larson, Theodore ; Punjani, Reshma ; Heller, Daniel ; Cohen, Jessica ; Peters, Tracy ; Muravov, Oleg ; Horton, Kevin
• Description:
  Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive and fatal neuromuscular disease; the majority of ALS patients die within 2-5 years of receiving a Diagnosis (1). Familial ALS, a hereditary form of the disease, accounts for 5%-10% of cases, whereas the remaining sporadic cases have no clearly defined etiology (1). ALS affects persons of all races and ethnicities; however, whites, males, non-Hispanics, persons aged >60 years, and those with a family History of ALS are more likely to develop the disease (1-3). No cure for ALS has yet been identified, and the lack of proven and effective therapeutic interventions is an ongoing challenge. Current treatments available do not cure ALS but have been shown to slow disease progression. Until recently, only one drug (riluzole) was approved to treat ALS; however, in 2017, the Food and Drug Administration approved a second drug, edaravone (4).
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Amyotrophic Lateral Sclerosis Female Full Report Humans Male Middle Aged Prevalence Registries Young Adult

  More +
• Source:
  MMWR Morbidity Mortal Weekly Rep. 67(7):216-218.
• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.mm6707a3
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Pubmed ID:
  29470458
• Pubmed Central ID:
  PMC5858037
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Pages in Document:
  3 pdf pages
• Volume:
  67
• Issue:
  7
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:1d2102c7600ba9fa2c5a6b76f6d54dafdfd8ecf6d016c345d8d79c6519bdb81a1e7ea43677447a23988df1445c8b814286b78a25d832b393560e18b041da298b
• Download URL:
  https://stacks.cdc.gov/view/cdc/53449/cdc_53449_DS1.pdf
• File Type:
  [PDF - 101.78 KB ]