Incidence of influenza‐associated mortality and hospitalizations in Argentina during 2002–2009

Details

• Alternative Title:
  Influenza Other Respir Viruses
• Personal Author:
  Azziz‐Baumgartner, Eduardo ; Cabrera, Ana María ; Cheng, Po‐Yung ; Garcia, Enio ; Kusznierz, Gabriela ; Calli, Rogelio ; Baez, Clarisa ; Buyayisqui, María Pía ; Poyard, Eleonora ; Pérez, Emanuel ; Basurto‐Davila, Ricardo ; Palekar, Rakhee ; Oliva, Otavio ; Alencar, Airlane Pereira ; de Souza, Regilo ; dos Santos, Thais ; Shay, David K. ; Widdowson, Marc‐Alain ; Breese, Joseph ; Echenique, Horacio
• Description:
  We estimated rates of influenza-associated deaths and hospitalizations in Argentina, a country that recommends annual influenza vaccination for persons at high risk of complications from influenza illness.|We identified hospitalized persons and deaths in persons diagnosed with pneumonia and influenza (P&I, ICD-10 codes J10-J18) and respiratory and circulatory illness (R&C, codes I00-I99 and J00-J99). We defined the influenza season as the months when the proportion of samples that tested positive for influenza exceeded the annual median. We used hospitalizations and deaths during the influenza off-season to estimate, using linear regression, the number of excess deaths that occurred during the influenza season. To explore whether excess mortality varied by sex and whether people were age <65 or ≥ 65 years, we used Poisson regression of the influenza-associated rates.|During 2002-2009, 2411 P&I and 8527 R&C mean excess deaths occurred annually from May to October. If all of these excess deaths were associated with influenza, the influenza-associated mortality rate was 6/100,000 person-years (95% CI 4-8/100,000 person-years for P&I and 21/100,000 person-years (95% CI 12-31/100,000 person-years) for R&C. During 2005-2008, we identified an average of 7868 P&I excess hospitalizations and 22,994 R&C hospitalizations per year, resulting in an influenza-associated hospitalization rate of 2/10,000 person-years (95% CI 1-3/10,000 person-years) for P&I and 6/10,000 person-years (95% CI 3-8/10,000 person-years) for R&C.|Our findings suggest that annual rates of influenza-associated hospitalizations and death in Argentina were substantial and similar to neighboring Brazil.
• Subjects:
  Aged Aged, 80 And Over Female Hospitalization Humans Incidence Influenza, Human Male
• Source:
  Influenza Other Respir Viruses. 7(5):710-717.
• Pubmed ID:
  23210456
• Pubmed Central ID:
  PMC5855154
• Document Type:
  Journal Article
• Place as Subject:
  Argentina
• Volume:
  7
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:49f3e83b4c7a908c6fd36b470e92fcf42fa7ca757b8b7a6647a49a1fd41caadf
• Download URL:
  https://stacks.cdc.gov/view/cdc/53446/cdc_53446_DS1.pdf
• File Type:
  [PDF - 410.58 KB ]