Hospital, Maternal, and Birth Factors Associated with Hepatitis B Vaccination at Birth — West Virginia, 2015

Details

• Alternative Title:
  Pediatr Infect Dis J
• Personal Author:
  Massey, Joel ; Nair, Anil ; Dietz, Stephanie ; Snaman, Deborah ; Bixler, Danae
• Description:
  Background
  
  Hepatitis B virus (HBV) is a bloodborne pathogen typically transmitted through sexual contact, injection drug use, or perinatally. A hepatitis B vaccine (HepB) is available; the first dose is recommended at birth. We sought to identify hospital policy, maternal characteristics, and birth factors associated with HepB receipt at birth in West Virginia (WV).
  
  Methods
  
  We conducted a retrospective cohort study of WV live births in 2015 using vital records matched to immunization registry records to determine frequency of HepB birth dose receipt (<3 days postdelivery). We surveyed all WV birthing facilities in 2015 (N = 26) about perinatal HBV prevention policies. We examined associations of hospital policy, maternal characteristics, and birth factors with HepB receipt at birth by using a mixed-effects regression model to calculate adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs).
  
  Results
  
  Of 17,458 births, 14,006 (80.2%) infants received a HepB birth dose. Hospital use of preprinted newborn routine admission vaccination orders was associated with HepB birth dose receipt (aPR 10.60; 95% CI, 2.12–52.72). Not using illicit drugs during pregnancy, maternal age <35 years, and weekday births were associated with HepB birth dose receipt (aPR 1.81, 95% CI, 1.54–2.13; aPR 1.34, 95% CI, 1.17–1.54; and aPR 1.15, 95% CI, 1.03–1.28, respectively).
  
  Conclusions
  
  Hospitals using preprinted admission orders had higher frequencies of HepB birth dose receipt. Additional study is needed to identify HepB birth dose receipt barriers among infants with maternal illicit drug use, maternal age ≥35 years, or deliveries during a weekend.
  
  
• Subjects:
  Adult Article Birth Dose Female Hepatitis B Hepatitis B Vaccines Hospital Policies Hospitals Humans Immunization Programs Infant, Newborn Legislation, Hospital Mothers Parturition Perinatal HepB Pregnancy Registries Retrospective Studies Surveys And Questionnaires Vaccination Vaccination Barriers West Virginia

  More +
• Source:
  Pediatr Infect Dis J. 37(7):691-696
• Pubmed ID:
  29462103
• Pubmed Central ID:
  PMC5894516
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHS/United States
• Volume:
  37
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:2aeb2e87d09bad09412768d1e9af3a07ebbce1bac3f19a88dd0e2da54fbdad50
• Download URL:
  https://stacks.cdc.gov/view/cdc/53394/cdc_53394_DS1.pdf
• File Type:
  [PDF - 176.17 KB ]