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Hospital, Maternal, and Birth Factors Associated with Hepatitis B Vaccination at Birth — West Virginia, 2015
  • Published Date:
    Jul 2018
  • Source:
    Pediatr Infect Dis J. 37(7):691-696.


Public Access Version Available on: July 01, 2019 information icon
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Details:
  • Pubmed ID:
    29462103
  • Pubmed Central ID:
    PMC5894516
  • Description:
    Background

    Hepatitis B virus (HBV) is a bloodborne pathogen typically transmitted through sexual contact, injection drug use, or perinatally. A hepatitis B vaccine (HepB) is available; the first dose is recommended at birth. We sought to identify hospital policy, maternal characteristics, and birth factors associated with HepB receipt at birth in West Virginia (WV).

    Methods

    We conducted a retrospective cohort study of WV live births in 2015 using vital records matched to immunization registry records to determine frequency of HepB birth dose receipt (<3 days postdelivery). We surveyed all WV birthing facilities in 2015 (N = 26) about perinatal HBV prevention policies. We examined associations of hospital policy, maternal characteristics, and birth factors with HepB receipt at birth by using a mixed-effects regression model to calculate adjusted prevalence ratios (aPRs) and 95% confidence intervals (CIs).

    Results

    Of 17,458 births, 14,006 (80.2%) infants received a HepB birth dose. Hospital use of preprinted newborn routine admission vaccination orders was associated with HepB birth dose receipt (aPR 10.60; 95% CI, 2.12–52.72). Not using illicit drugs during pregnancy, maternal age <35 years, and weekday births were associated with HepB birth dose receipt (aPR 1.81, 95% CI, 1.54–2.13; aPR 1.34, 95% CI, 1.17–1.54; and aPR 1.15, 95% CI, 1.03–1.28, respectively).

    Conclusions

    Hospitals using preprinted admission orders had higher frequencies of HepB birth dose receipt. Additional study is needed to identify HepB birth dose receipt barriers among infants with maternal illicit drug use, maternal age ≥35 years, or deliveries during a weekend.

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