Guidance for Laboratory Biomonitoring Programs: Developing Biomonitoring Capabilities
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April 2012
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English
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Alternative Title:Guidance for biomonitoring programs
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Description:The goals of this guidance are to outline the infrastructure and expertise needed to develop laboratory capacity for a biomonitoring program and to highlight some of the main considerations chemists should address before beginning a biomonitoring study, which include the need to: ; • Define the goals of a biomonitoring study; ; • Choose the appropriate biomarker in the appropriate matrix at a suf cient level of sensitivity; ; • Identify resource needs and sources of potential funding; ; • Collaborate with epidemiologists and toxicologists in the development of the study design and to analyze and communicate biomonitoring data; ; • Produce reliable, valid and comparable data; ; • Engage the community early in the study design process; and ; • Develop an effective communication plan that involves reporting of individual results (if appropriate), aggregate data and access to public health, citizens or medical professionals for results distribution and interpretation. ; While the technology and instrumentation used for biomonitoring testing have a lot in common with environmental testing laboratories, biomonitoring presents a set of unique challenges. Assaying clinical matrices involves the safe handling of potentially infectious materials, different interferences, and possibly the analysis of metabolites. The greatest differences between bio- monitoring and environmental testing involve the interpretation of clinical ndings and effective communication of results on an individual and community basis. ; EH_2012_Guidance-for-Laboratory-Biomonitoring-Programs.pdf ; Running title: Guidance for biomonitoring programs. ; This report was supported 100% by Cooperative Agreement Number #U60/CD303019 from Centers for Disease Con- trol and Prevention (“CDC”). Its contents are solely the responsibility of the authors and do not necessarily represent the of cial views of CDC.
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Pages in Document:79 numbered pages
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Main Document Checksum:urn:sha-512:1bd89f030d4158816b0c11c24593b512252d8a0573008fd07429260fb3d501bc825b0c2ea17c45446d3ce3127dd149436b246dbef8fa9fe651ad72789e99a13c
File Language:
English
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