Welcome to CDC stacks |

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Evaluation of the Cepheid Xpert MTB/RIF assay

Published Date:

Nov 06 2014

Source:

Expert Rev Mol Diagn. 15(1):9-22.

Language:

English

[PDF-811.60 KB]

Details:

Alternative Title:

Expert Rev Mol Diagn

Personal Author:

Shinnick, Thomas M. ; Starks, Angela M. ; Alexander, Heather L. ; Castro, Kenneth G. ;

Description:

The lack of capacity to provide laboratory confirmation of a diagnosis of tuberculosis disease (TB) is contributing to enormous gaps in the ability to find, treat and follow TB patients. WHO estimates that globally only about 57% of the notified new cases of pulmonary TB in 2012 and about 19% of rifampicin-resistant TB cases were laboratory confirmed. The Cepheid Xpert(®) MTB/RIF assay has been credited with revolutionizing laboratory testing to aid in the diagnosis of TB and rifampicin-resistant TB. This semi-automated test can detect both the causative agent of TB and mutations that confer rifampicin resistance from clinical specimens within 2 h after starting the test. In this article, we review the performance of the test, its pathway to regulatory approval and endorsement, guidelines for its use and lessons learned from the implementation of the test in low-burden, high-resource countries and in high-burden, low-resource countries.

Subject:

[+]

Pubmed ID:

25373876

Pubmed Central ID:

PMC5875728

Document Type:

Journal Article

Funding:

CC999999/Intramural CDC HHS/United States

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	nihms933116.nxml	text/xml
	nihms933116f1.gif	image/gif
	nihms933116f1.jpg	image/jpeg
	nihms933116f2.gif	image/gif
	nihms933116f2.jpg	image/jpeg

No Related Documents.

You May Also Like:

Interim guidance for use of pooling procedures in SARS-CoV-2 diagnostic, screening, and surveillance testing

Corporate Authors:

National Center for Immunization and Respiratory Diseases (U.S.). Division of Viral Diseases.

Published Date:

August 1, 2020

Description:

Updated Aug. 1, 2020Note: This document provides guidance on the appropriate use of testing and does not dictate the determination of payment decisions or insurance coverage of such testing, except as may be otherwise referenced (or prescribed) by an...

File Type:

[PDF - 218.76 KB]
Essential Components of a Public Health Tuberculosis Prevention, Control, and Elimination Program: Recommendations of the Advisory Council for the Elimination of Tuberculosis and the National Tuberculosis Controllers Association. MMWR Recomm Rep 2020;69(No. RR-7).

Personal Author:

Cole B, Nilsen DM, Will L, et al.

Published Date:

07/31/2020

Source:

MMWR Recomm Rep 2020;69(No. RR-7)

Series:

MMWR Recommendations and Reports

Description:

SUPPLEMENTARY APPENDIX A: Responsibilities of the Tuberculosis Controller or Tuberculosis Program Manager; SUPPLEMENTARY APPENDIX B: Core Public Health Functions and Essential Services; SUPPLEMENTARY APPENDIX C: CDC-Funded Resources; SUPPLEMENTARY AP...

File Type:

[PDF - 698.42 KB]
Progress Toward Hepatitis B Control — South-East Asia Region, 2016–2019

Personal Author:

Sandhu, Hardeep S.; Roesel, Sigrun; Sharifuzzaman, Mohammad; Chunsuttiwat, Supamit; Tohme, Rania A.;

Published Date:

July 31 2020

Source:

MMWR Morb Mortal Wkly Rep. 69(30):988-992

Description:

In 2015, the World Health Organization (WHO) South-East Asia Region (SEAR)* reported an estimated 40 million persons living with chronic hepatitis B virus (HBV) infection and 285,000 deaths from complications of chronic infection, cirrhosis, and hepa...

File Type:

[PDF - 300.60 KB]
Notes from the Field: Rebound in Routine Childhood Vaccine Administration Following Decline During the COVID-19 Pandemic — New York City, March 1–June 27, 2020

Personal Author:

Langdon-Embry, Marisa; Papadouka, Vikki; Cheng, Iris; Almashhadani, Mohammed; Ternier, Alexandra; Zucker, Jane R.;

Published Date:

July 31 2020

Source:

MMWR Morb Mortal Wkly Rep. 69(30):999-1001

File Type:

[PDF - 100.43 KB]
Notes from the Field: Public Health Efforts to Mitigate COVID-19 Transmission During the April 7, 2020, Election ― City of Milwaukee, Wisconsin, March 13–May 5, 2020

Personal Author:

Paradis, Heather; Katrichis, Julie; Stevenson, Michael; Tomaro, Nicholas; Mukai, Rachel; Torres, Griselle; Bhattacharyya, Sanjib; Kowalik, Jeanette; Schlanger, Karen; Leidman, Eva;

Published Date:

July 31 2020

Source:

MMWR Morb Mortal Wkly Rep. 69(30):1002-1003

File Type:

[PDF - 93.78 KB]