Hot topics in antifungal susceptibility testing: A new drug, a bad bug, sweeping caspofungin testing under the rug, and solving the ECV shrug

Details

• Alternative Title:
  Clin Microbiol Newsl
• Personal Author:
  Lockhart, Shawn R. ; Berkow, Elizabeth L.
• Description:
  There are several new hot topics in antifungals and antifungal susceptibility testing. In this review, four topics of general interest to the clinical microbiology community are discussed. The first topic is the introduction of isavuconazole, a new triazole approved for clinical use in the US. The second is triazole resistance in | isolates. A specific set of mutations are being found with greater frequency in isolates globally, including the US. The third topic of interest is a word of caution about antifungal susceptibility testing for caspofungin in | isolates; some laboratories have reported susceptible isolates with high MIC values that would be interpreted as resistant. The final topic is an introduction to epidemiological cutoff values and their use in the clinical mycology laboratory.
• Subjects:
  Article
• Source:
  Clin Microbiol Newsl. 38(13):103-108
• Pubmed ID:
  29545657
• Pubmed Central ID:
  PMC5849271
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  38
• Issue:
  13
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:43883a775a4db568b2065e9773f432305b57404fe4c54814ce9c251fb578ccd9
• Download URL:
  https://stacks.cdc.gov/view/cdc/52740/cdc_52740_DS1.pdf
• File Type:
  [PDF - 405.62 KB ]