Details:

Alternative Title:
Am J Prev Med
Personal Author:
Trogdon, Justin G. ; Ekwueme, Donatus U. ; Chamiec-Case, Linda ; Guy, Gery P.
Trogdon, Justin G. ; Ekwueme, Donatus U. ; Chamiec-Case, Linda ; Guy, Gery P. Less -
Description:
Introduction

Little is known about the effect of breast cancers on health-related quality of life among women diagnosed between age 18 and 44 years. The goal of this study is to estimate the effect of breast cancer on health state utility by age at diagnosis (18–44 years versus ≥45 years) and by race/ethnicity.

Methods

The analytic sample, drawn from the 2009 and 2010 Behavioral Risk Factor Surveillance System and analyzed in 2013, included women diagnosed with breast cancer between age 18 and 44 years (n=1,389) and age ≥45 years (n=6,037). Health state utility values were estimated using Healthy Days variables and a published algorithm. Regression analysis was conducted separately by age at diagnosis and race/ethnicity.

Results

The breast cancer health state utility decrement within 1 year from date of diagnosis was larger for women diagnosed at age 18–44 years than for women diagnosed at age ≥45 years (−0.116 vs −0.070, p<0.05). Within the younger age-at-diagnosis group, Hispanic women 2–4 years after diagnosis had the largest health state utility decrement (−0.221, p<0.01), followed by non-Hispanic white women within 1 year of diagnosis (−0.126, p<0.01).

Conclusions

This study is the first to report estimates of health state utility values for breast cancer by age at diagnosis and race/ethnicity from a nationwide sample. The results highlight the need for separate quality of life adjustments for women by age at diagnosis and race/ethnicity when conducting cost-effectiveness analysis of breast cancer prevention, detection, and treatment.


Subject:
[+]
Adolescent
Adult
Aged
Age Factors
Breast Neoplasms
Comorbidity
Cost Of Illness
Costs And Cost Analysis
Ethnicity
Female
Health Status
Humans
Mental Health
Middle Aged
Quality Of Life
Racial Groups
Socioeconomic Factors
Women's Health
Young Adult

Source:
Am J Prev Med. 50(2):262-269.
Pubmed ID:
26775905
Pubmed Central ID:
PMC5841540
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States ; 200-2008-27958 TASK ORDER 0026/PHS HHS/United States
CC999999/Intramural CDC HHS/United States ; 200-2008-27958 TASK ORDER 0026/PHS HHS/United States Less -
Name as Subject:
Behavioral Risk Factor Surveillance System ; Behavioral Risk Factor Surveillance System
Behavioral Risk Factor Surveillance System ; Behavioral Risk Factor Surveillance System Less -
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f8badaa3979e00a13b712558760f9019dae4fec1eff7ea180d04d2159518be2c
File Type:

Supporting Files

• 	NIHMS946244-supplement-Appendix.pdf	pdf
  	nihms946244.nxml	xml
  	nihms946244f1.gif	gif
  	nihms946244f1.jpg	jpeg

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