Perspectives and Concerns Regarding Antimicrobial Agent Shortages Among Infectious Disease Specialists

Gundlapalli, Adi V.; Beekmann, Susan E.; Graham, Donald R.; Polgreen, Philip M.

doi:10.1016/j.diagmicrobio.2012.11.020

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Perspectives and Concerns Regarding Antimicrobial Agent Shortages Among Infectious Disease Specialists

Published Date:

Jan 08 2013

Publisher's site:

http://dx.doi.org/10.1016/j.diagmicrobio.2012.11.020 New Site Icon

Source:

Diagn Microbiol Infect Dis. 75(3):256-259.

[PDF-57.88 KB]

Details:

Alternative Title:

Diagn Microbiol Infect Dis

Personal Author:

Gundlapalli, Adi V. ; Beekmann, Susan E. ; Graham, Donald R. ; Polgreen, Philip M. ;

Description:

Antimicrobial shortages have made treating certain infections more difficult. A web-based survey asking about experience with antimicrobial drug shortages was distributed in 2011 to 1328 infectious diseases physician members of the Emerging Infectious Diseases Network of the Infectious Diseases Society of America. A majority (78%) of 627 respondents reported needing to modify antimicrobial choices because of drug shortages within the past 2 years. Antimicrobials most often reported as not available or available but in short supply were trimethoprim-sulfamethoxazole injection (by 65% of respondents), amikacin (by 58%), aztreonam (by 31%), and foscarnet (by 22%). Most respondents (55%) reporting a shortage indicated that the shortage adversely affected patient outcomes and that they were forced to use alternative and second line agents which were either less effective, more toxic, or more costly. Most (70%) indicated that they learned about the shortage from contact with the pharmacy after trying to prescribe a drug in short supply. More effective means of informing physicians about drug shortages is critical to lessen the impact on patient care.

Subject:

[+]

Pubmed ID:

23305775

Pubmed Central ID:

PMC5815827

Document Type:

Journal Article

Funding:

U50 CCU112346/PHS HHS/United States ; 5P01HK000069/HK/PHITPO CDC HHS/United States ; 1 U54 A1065357/PHS HHS/United States ; U54 AI065357/AI/NIAID NIH HHS/United States ; P01 HK000069/HK/PHITPO CDC HHS/United States ;

Collection(s):

CDC Public Access

Main Document Checksum:

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Supporting Files:

nihms-426589.nxml

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