Maternal and Paternal Infertility Disorders and Treatments and Autism Spectrum Disorder: Findings from the Study to Explore Early Development

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  Schieve, Laura A. ; Drews-Botsch, Carolyn ; Harris, Shericka ; Newschaffer, Craig ; Daniels, Julie ; DiGuiseppi, Carolyn ; Croen, Lisa A. ; Windham, Gayle C.
• Description:
  Previous studies of associations between ASD and conception using assisted reproductive technology (ART) are inconsistent and few studies have examined associations with other infertility treatments or infertility disorders. We examined associations between ASD and maternal/paternal infertility disorders and numerous maternal treatments among 1538 mother-child pairs in the Study to Explore Early Development, a population-based case-control study. ASD was associated with any female infertility diagnosis and several specific diagnoses: blocked tubes, endometriosis, uterine-factor infertility, and polycystic ovarian syndrome. Stratified analyses suggested associations were limited to/much stronger among second or later births. The findings were not explained by sociodemographic factors such as maternal age or education or multiple or preterm birth. ASD was not associated with ART or non-ART infertility treatments.
• Keywords:
  Adult Assisted Autism Spectrum Disorder Case-Control Studies Child Epidemiology Female Humans Infant, Newborn Infertility Infertility, Female Infertility, Male Male Neurodevelopmental Disorders Ovulation Induction Pregnancy Prenatal Exposure Delayed Effects Reproductive Techniques Reproductive Techniques, Assisted Risk Factors Young Adult

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• Source:
  J Autism Dev Disord. 47(12):3994-4005
• Pubmed ID:
  28900768
• Pubmed Central ID:
  PMC5804352
• Document Type:
  Journal Article
• Funding:
  U10 DD000180/DD/NCBDD CDC HHSUnited States/ ; U10 DD000181/DD/NCBDD CDC HHSUnited States/ ; U10 DD000184/DD/NCBDD CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U10 DD000182/DD/NCBDD CDC HHSUnited States/ ; U10 DD000183/DD/NCBDD CDC HHSUnited States/ ; U01 DD001210/DD/NCBDD CDC HHSUnited States/ ; U01 DD000498/DD/NCBDD CDC HHSUnited States/
• Volume:
  47
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:db9c472aa1aca5fd6c94ad2ad7a8d37b6664b711411f5c7c55532ab58d875dc764645060b134d15d541bab700085abc5539b889998ebd06dda89d9dcdb2fdd7b
• Download URL:
  https://stacks.cdc.gov/view/cdc/51521/cdc_51521_DS1.pdf
• File Type:
  [PDF - 106.48 KB ]