Validation of self-reported comorbidity status of breast cancer patients with medical records: the California Breast Cancer Survivorship Consortium (CBCSC)

Details

• Alternative Title:
  Cancer Causes Control
• Personal Author:
  Vigen, Cheryl ; Kwan, Marilyn L. ; John, Esther M. ; Gomez, Scarlett Lin ; Keegan, Theresa H. M. ; Lu, Yani ; Shariff-Marco, Salma ; Monroe, Kristine R. ; Kurian, Allison W. ; Cheng, Iona ; Caan, Bette J. ; Lee, Valerie S. ; Roh, Janise M. ; Bernstein, Leslie ; Sposto, Richard ; Wu, Anna H.
• Description:
  Purpose
  
  To compare information from self-report and electronic medical records for four common comorbidities (diabetes, hypertension, myocardial infarction, and other heart diseases).
  
  Methods
  
  We pooled data from two multiethnic studies (one case–control and one survivor cohort) enrolling 1,936 women diagnosed with breast cancer, who were members of Kaiser Permanente Northern California.
  
  Results
  
  Concordance varied by comorbidity; kappa values ranged from 0.50 for other heart diseases to 0.87 for diabetes. Sensitivities for comorbidities from self-report versus medical record were similar for racial/ethnic minorities and non-Hispanic Whites, and did not vary by age, neighborhood socioeconomic status, or education. Women with a longer history of comorbidity or who took medications for the comorbidity were more likely to report the condition. Hazard ratios for all-cause mortality were not consistently affected by source of comorbidity information; the hazard ratio was lower for diabetes, but higher for the other comorbidities when medical record versus self-report was used. Model fit was better when the medical record versus self-reported data were used.
  
  Conclusions
  
  Comorbidities are increasingly recognized to influence the survival of patients with breast or other cancers. Potential effects of misclassification of comorbidity status should be considered in the interpretation of research results.
  
  
• Subjects:
  Breast Neoplasms/epidemiology Comorbidity Electronic Health Records Ethnicity Female Humans Middle Aged Proportional Hazards Models Racial Groups Residence Characteristics Self Report Survival Rate Survivors White People

  More +
• Source:
  Cancer Causes Control. 27(3):391-401.
• Pubmed ID:
  26797455
• Pubmed Central ID:
  PMC5792190
• Document Type:
  Journal Article
• Funding:
  HHSN261201000034C/PHS HHS/United States ; UM1 CA164973/CA/NCI NIH HHS/United States ; U58DP003862-01/DP/NCCDPHP CDC HHS/United States ; HHSN261201000035C/PC,CA/None/None ; HHSN261201000140C/CA/NCI NIH HHS/United States ; HHSN261201000035C/PHS HHS/United States ; R01CA63446/CA/NCI NIH HHS/United States ; K05CA136967/CA/NCI NIH HHS/United States ; R01 CA129059/CA/NCI NIH HHS/United States ; UM1CA164973/CA/NCI NIH HHS/United States ; K05 CA136967/CA/NCI NIH HHS/United States ; R01CA77305/CA/NCI NIH HHS/United States ; HHSN261201000035I/CA/NCI NIH HHS/United States ; R01 CA063446/CA/NCI NIH HHS/United States ; R01 CA077398/CA/NCI NIH HHS/United States ; R01 CA054281/CA/NCI NIH HHS/United States ; R01 CA77398/CA/NCI NIH HHS/United States ; HHSN261201000034C/CA/NCI NIH HHS/United States ; R37CA54281/CA/NCI NIH HHS/United States ; U58 DP003862/DP/NCCDPHP CDC HHS/United States ; HHSN261201000140C/PHS HHS/United States ; R01CA54281/CA/NCI NIH HHS/United States ; R37 CA054281/CA/NCI NIH HHS/United States ; N01-HD-3-3175/HD/NICHD NIH HHS/United States
• Place as Subject:
  California
• Volume:
  27
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:88ef4b093173a0d0c5f74a1a6b20c947334e7eacc295ecfd02b5406913c1b88a
• Download URL:
  https://stacks.cdc.gov/view/cdc/51296/cdc_51296_DS1.pdf
• File Type:
  [PDF - 125.68 KB ]