Diagnosis and Treatment of Clostridium difficile Infection (CDI)

Details

• Alternative Title:
  Infect Dis Clin Pract (Baltim Md)
• Personal Author:
  Gerding, Dale N. ; File, Thomas M. ; McDonald, L. Clifford
• Description:
  Early and accurate diagnosis is essential for optimal treatment of individuals with | infection (CDI) and for implementation of effective infection control procedures. The decision about which diagnostic test to use is an important one that should be based on test sensitivity, specificity, and predictive value. The challenges of CDI go beyond rapid identification and management of symptomatic patients. Asymptomatic carriage has long been suspected in | transmission, but it may play a larger role than previously thought. Emerging information also shows that patients treated for CDI remain colonized for many weeks after symptom resolution. In fact, stool culture positivity increases during the first weeks following treatment completion. Treatments that reduce the duration and degree of asymptomatic shedding could have added benefit for reduced transmission.
• Keywords:
  CDI Clostridium Difficile Diagnostic Test Treatment
• Source:
  Infect Dis Clin Pract (Baltim Md). 24(1):3-10
• Pubmed ID:
  29348706
• Pubmed Central ID:
  PMC5769958
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  24
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:8f4909a3ba0dee96412b02504f3d3ae4690fbb644ff26f16c1a8eaacb991b0c0
• Download URL:
  https://stacks.cdc.gov/view/cdc/51146/cdc_51146_DS1.pdf
• File Type:
  [PDF - 151.55 KB ]