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Trends in Risk of Pregnancy Loss Among US Women, 1990–2011

Filetype[PDF-475.58 KB]


  • English
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    Details:

    • Alternative Title:
      Paediatr Perinat Epidemiol
    • Personal Author:
    • Description:
      Background

      Pregnancy loss can have physical and psychological consequences for women and their families. Though a previous study described an increase in the risk of self-reported pregnancy loss from 1970 to 2000, more recent examinations from population-based data of US women are lacking.

      Methods

      We used data from the 1995, 2002, 2006–2010, 2011–2015 National Survey of Family Growth on self-reported pregnancy loss (miscarriage, stillbirth, ectopic pregnancy) among US women (15–44 years) who reported at least one pregnancy conceived during 1990–2011 that did not result in induced termination (n = 20 012 women; n = 42 526 pregnancies). Trends in the risk of self-reported pregnancy loss and early pregnancy loss (<12 weeks) were estimated, separately, by year of pregnancy conception (limited to 1990–2011 to ensure a sufficient sample of pregnancies for each year and maternal age group) using log-Binomial and Poisson models, adjusted for maternal- and pregnancy-related factors.

      Results

      Among all self-reported pregnancies, excluding induced terminations, the risk of pregnancy loss was 19.7% and early pregnancy loss was 13.5% during 1990–2011. Risk of pregnancy loss increased by a relative 2% (rate ratio [RR] 1.02, 95% confidence interval [CI] 1.01, 1.02) per year in unadjusted models and 1% per year (RR 1.01, 95% CI 1.00, 1.02) during 1990–2011, after adjustment for maternal characteristics and pregnancy-related factors. In general, trends were similar for early pregnancy loss.

      Conclusion

      From 1990 to 2011, risk of self-reported pregnancy loss increased among US women. Further work is needed to better understand the drivers of this increase in reported pregnancy loss in the US.

    • Subjects:
    • Source:
      Paediatr Perinat Epidemiol. 32(1):19-29
    • Pubmed ID:
      29053188
    • Pubmed Central ID:
      PMC5771868
    • Document Type:
      Journal Article
    • Funding:
      CC999999/ImCDC/Intramural CDC HHS/United States
    • Place as Subject:
      United States
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