Details:

Alternative Title:
J Expo Sci Environ Epidemiol
Personal Author:
Chiu, Yu-Han ; Williams, Paige L. ; Mínguez-Alarcón, Lidia ; Gillman, Matthew ; Sun, Qi ; ... More +
Chiu, Yu-Han ; Williams, Paige L. ; Mínguez-Alarcón, Lidia ; Gillman, Matthew ; Sun, Qi ; Ospina, Maria ; Calafat, Antonia M. ; Hauser, Russ ; Chavarro, Jorge E. Less -
Corporate Authors:
for the EARTH Study Team
Description:
We developed a pesticide residue burden score (PRBS) based on a food frequency questionnaire and surveillance data on food pesticide residues to characterize dietary exposure over the past year. In the present study, we evaluated the association of the PRBS with urinary concentrations of pesticide biomarkers. Fruit and vegetable (FV) intake was classified as having high (PRBS≥4) or low (PRBS<4) pesticide residues for 90 men from the EARTH study. Two urine samples per man were analyzed for seven biomarkers of organophosphate and pyrethroid insecticides, and the herbicide 2,4-dichlorophenoxyacetic acid. We used generalized estimating equations to analyze the association of the PRBS with urinary concentrations of pesticide biomarkers. Urinary concentrations of pesticide biomarkers were positively related to high pesticide FV intake but inversely related to low pesticide FV intake. The molar sum of urinary concentrations of pesticide biomarkers was 21% (95% confidence interval (CI): 2%, 44%) higher for each one serving/day increase in high pesticide FV intake, and 10% (95% CI: 1%, 18%) lower for each one serving/day increase in low pesticide FV intake. Furthermore, intake of high pesticide FVs positively related to most individual urinary biomarkers. Our findings support the usefulness of the PRBS approach to characterize dietary exposure to select pesticides.
Subjects:
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Adult Article Biomarkers Biomonitoring Dietary Exposure Diet Surveys Environmental Exposure Fruit Humans Longitudinal Studies Male Massachusetts Middle Aged Organophosphates Pesticide Residues Pesticides Pyrethrins Surveys And Questionnaires Vegetables
Source:
J Expo Sci Environ Epidemiol. 28(1):31-39
Pubmed ID:
28930298
Pubmed Central ID:
PMC5734986
Document Type:
Journal Article
Funding:
R01 ES021372/ES/NIEHS NIH HHS/United States ; P30 ES000002/ES/NIEHS NIH HHS/United States ; R01 ES009718/ES/NIEHS NIH HHS/United States ; P30 DK046200/DK/NIDDK NIH HHS/United States ; CC999999/ImCDC/Intramural CDC HHS/United States ; ... More +
R01 ES021372/ES/NIEHS NIH HHS/United States ; P30 ES000002/ES/NIEHS NIH HHS/United States ; R01 ES009718/ES/NIEHS NIH HHS/United States ; P30 DK046200/DK/NIDDK NIH HHS/United States ; CC999999/ImCDC/Intramural CDC HHS/United States ; R01 ES022981/ES/NIEHS NIH HHS/United States ; R01 ES022955/ES/NIEHS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d81ac3b3cf361f2366b46d9291d5e1992256db651ba8920a2ca79e7b4461baab
Download URL:
https://stacks.cdc.gov/view/cdc/50574/cdc_50574_DS1.pdf
File Type:

Supporting Files

• 	NIHMS915996-supplement-Supplemental_Info.doc	doc
  	nihms915996.nxml	xml
  	nihms915996f1.gif	gif
  	nihms915996f1.jpg	jpeg
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