Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers

Chiu, Yu-Han; Williams, Paige L.; Mínguez-Alarcón, Lidia; Gillman, Matthew; Sun, Qi; Ospina, Maria; Calafat, Antonia M.; Hauser, Russ; Chavarro, Jorge E.

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Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers

Published Date:

Sep 20 2017

Source:

J Expo Sci Environ Epidemiol. 28(1):31-39

Language:

English

[PDF-1.03 MB]

Details:

Alternative Title:

J Expo Sci Environ Epidemiol

Personal Author:

Chiu, Yu-Han ; Williams, Paige L. ; Mínguez-Alarcón, Lidia ; Gillman, Matthew ; Sun, Qi ; ... More ▼

Corporate Authors:

for the EARTH Study Team

Description:

We developed a pesticide residue burden score (PRBS) based on a food frequency questionnaire and surveillance data on food pesticide residues to characterize dietary exposure over the past year. In the present study, we evaluated the association of the PRBS with urinary concentrations of pesticide biomarkers. Fruit and vegetable (FV) intake was classified as having high (PRBS≥4) or low (PRBS<4) pesticide residues for 90 men from the EARTH study. Two urine samples per man were analyzed for seven biomarkers of organophosphate and pyrethroid insecticides, and the herbicide 2,4-dichlorophenoxyacetic acid. We used generalized estimating equations to analyze the association of the PRBS with urinary concentrations of pesticide biomarkers. Urinary concentrations of pesticide biomarkers were positively related to high pesticide FV intake but inversely related to low pesticide FV intake. The molar sum of urinary concentrations of pesticide biomarkers was 21% (95% confidence interval (CI): 2%, 44%) higher for each one serving/day increase in high pesticide FV intake, and 10% (95% CI: 1%, 18%) lower for each one serving/day increase in low pesticide FV intake. Furthermore, intake of high pesticide FVs positively related to most individual urinary biomarkers. Our findings support the usefulness of the PRBS approach to characterize dietary exposure to select pesticides.

Subject:

[+]

Pubmed ID:

28930298

Pubmed Central ID:

PMC5734986

Document Type:

Journal Article

Funding:

R01 ES021372/ES/NIEHS NIH HHS/United States ; P30 ES000002/ES/NIEHS NIH HHS/United States ; R01 ES009718/ES/NIEHS NIH HHS/United States ; P30 DK046200/DK/NIDDK NIH HHS/United States ; CC999999/ImCDC/Intramural CDC HHS/United States ; ... More ▼

Collection(s):

CDC Public Access

Main Document Checksum:

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File Type:

Supporting Files:

	NIHMS915996-supplement-Supplemental_Info.doc	application/msword
	nihms915996.nxml	text/xml
	nihms915996f1.gif	image/gif
	nihms915996f1.jpg	image/jpeg
	nihms915996f2.gif	image/gif
	nihms915996f2.jpg	image/jpeg

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Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers

Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers

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