Incidence of symptomatic A(H1N1)pdm09 influenza during the pandemic and post-pandemic periods in a rural Indian community

Details

• Alternative Title:
  Int J Infect Dis
• Personal Author:
  Fowler, Karen B. ; Gupta, Vivek ; Sullender, Wayne ; Broor, Shobha ; Widdowson, Marc-Alain ; Lal, Renu B. ; Krishnan, Anand
• Description:
  Background
  
  Data on influenza illness rates with population denominators are needed to quantify overall morbidity and to prioritize public health intervention strategies.
  
  Methods
  
  The rates of influenza A(H1N1)pdm09 infection during pandemic phases were determined in a longitudinal community cohort study as part of an influenza vaccine study in a rural community of North India.
  
  Results
  
  During the 711 731 person-weeks of surveillance, a total of 1410/7571 (19%) febrile acute respiratory illness cases were positive for influenza. Of these, 749 (53%) were influenza A(H1N1)pdm09, 643 (46%) influenza B, and 18 (1%) influenza A (H3N2). The overall incidence rate of influenza-associated febrile acute respiratory illness was 128/1000 person-years. The incidence rates of influenza A(H1N1)pdm09 were high during both the pandemic phase (179/1000 person-years; November 2009 to January 2010) and post-pandemic phase (156/1000 person-years; August to October 2010), with children <18 years of age being at the greatest risk of influenza infection in the community.
  
  Conclusions
  
  These findings provide important information for planning clinical and public health intervention strategies to mitigate the impact of influenza epidemics.
  
  
• Subjects:
  Adolescent Adult Aged Age Factors Article Child Child, Preschool Cohort Epidemiology Female Humans Incidence India Infant Infant, Newborn Influenza, Human Influenza A(H1N1)pdm09 Influenza A Virus, H1N1 Subtype Male Middle Aged Population Surveillance Rural India Rural Population Young Adult

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• Source:
  Int J Infect Dis. 17(12):e1182-e1185
• Pubmed ID:
  24103331
• Pubmed Central ID:
  PMC5733120
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/ ; U01 IP000177/IP/NCIRD CDC HHSUnited States/
• Volume:
  17
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:70aa6704e695566b9fc5e5c622b3d67023ca6f689c99952aefa75dcc148239a2
• Download URL:
  https://stacks.cdc.gov/view/cdc/50562/cdc_50562_DS1.pdf
• File Type:
  [PDF - 444.81 KB ]