Time-Varying Effects of Parental Alcoholism on Depression

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Thapa, Sunita ; Selya, Arielle S. ; Jonk, Yvonne
• Description:
  Introduction
  
  Children of alcoholic parents are at increased risk for lifetime depression. However, little is known about how this risk may change in magnitude across age, especially in mid-adulthood and beyond.
  
  Methods
  
  We used a nationally representative sample (N = 36,057) of US adults from the National Epidemiologic Survey on Alcohol and Related Conditions, wave III. After adjusting for demographic characteristics, we examined the relationship between parental alcoholism and outcomes of 1) major depressive disorder, Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) and 2) DSM-5 persistent depressive disorder. To examine continuous moderation of this relationship across participants’ age, we used time-varying effect models.
  
  Results
  
  Parental alcoholism was associated in general with a higher risk for both major depressive disorder (odds ratio [OR], 1.98, 95% confidence interval [CI], 1.85–2.11; P < .001) and persistent depressive disorder (OR, 2.28, 95% CI, 2.04–2.55; P < .001). The association between parental alcoholism and major depressive disorder was stable and positive across age, but the association with persistent depressive disorder significantly declined among older adults; respondents older than 73 years old were not at increased risk for persistent depressive disorder.
  
  Conclusions
  
  Findings from this study show that the risk of parental alcoholism on depression is significant and stable among individuals of a wide age range, with the exception of a decline in persistent depressive risk among older adults. These findings highlight the importance of screening for depression among adults with parental alcoholism.
  
  
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Alcoholism Child Of Impaired Parents Depressive Disorder Female Humans Male Middle Aged Odds Ratio Parent-Child Relations Risk Factors Young Adult

  More +
• Source:
  Prev Chronic Dis. 14.
• DOI:
  http://dx.doi.org/10.5888/pcd14.170100
• ISSN:
  1545-1151
• Pubmed ID:
  29240551
• Pubmed Central ID:
  PMC5737982
• Document Type:
  Journal Article
• Volume:
  14
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:36dfd38058d6a677147c0d488e5aa5e1087751e114ec674369e89d58f6f0afdf3fb2a9f626957b717b0905ba92c3f962fb2678fc2ca594fc4b40c9dc25afd9c8
• Download URL:
  https://stacks.cdc.gov/view/cdc/50363/cdc_50363_DS1.pdf
• File Type:
  [PDF - 292.10 KB ]