HIV Transmission Dynamics among Foreign-born Persons in the United States

Details

• Alternative Title:
  J Acquir Immune Defic Syndr
• Personal Author:
  Valverde, Eduardo E. ; Oster, Alexandra M. ; Xu, Songli ; Wertheim, Joel O. ; Hernandez, Angela L.
• Description:
  Background
  
  In the United States (U.S.), foreign-born persons are disproportionately affected by HIV and differ epidemiologically from U.S.-born persons with diagnosed HIV infection. Understanding HIV transmission dynamics among foreign-born persons is important to guide HIV prevention efforts for these populations. We conducted molecular transmission network analysis to describe HIV transmission dynamics among foreign-born persons with diagnosed HIV.
  
  Methods
  
  Using HIV-1 polymerase nucleotide sequences reported to the U.S. National HIV Surveillance System for persons with diagnosed HIV infection during 2001–2013, we constructed a genetic distance based transmission network using HIV-TRACE and examined the birth region of potential transmission partners in this network.
  
  Results
  
  Of 77,686 people, 12,064 (16%) were foreign-born. Overall, 28% of foreign-born persons linked to at least one other person in the transmission network. Of potential transmission partners, 62% were born in the United States, 31% were born in the same region as the foreign-born person, and 7% were born in another region of the world. The majority of transmission partners of male foreign-born persons (63%) were born in the United States, whereas the majority of transmission partners of female foreign-born (57%) were born in their same world region.
  
  Discussion
  
  These finding suggests that a majority of HIV infections among foreign-born persons in our network occurred after immigrating to the United States. Efforts to prevent HIV infection among foreign-born persons in the U.S. should include information of the transmission networks in which these individuals acquire or transmit HIV in order to develop more targeted HIV prevention interventions.
  
  
• Subjects:
  Adolescent Adult Article Emigrants And Immigrants Female Foreign-born HIV HIV Infections Humans Male Middle Aged Molecular Transmission United States Young Adult

  More +
• Source:
  J Acquir Immune Defic Syndr. 76(5):445-452.
• Pubmed ID:
  28902072
• Pubmed Central ID:
  PMC5680123
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States ; K01 AI110181/AI/NIAID NIH HHS/United States
• Volume:
  76
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:720a6101a5ee221cc845eeb0054a6b226ee23fe67b6c6d34097f2cf5aedca631
• Download URL:
  https://stacks.cdc.gov/view/cdc/49706/cdc_49706_DS1.pdf
• File Type:
  [PDF - 148.27 KB ]