Unique Presentation of Orf Virus Infection in a Thermal-Burn Patient After Receiving an Autologous Skin Graft

Details

• Alternative Title:
  J Infect Dis
• Personal Author:
  Hsu, Christopher H. ; Rokni, Ghasem Rahmatpour ; Aghazadeh, Nessa ; Brinster, Nooshin ; Li, Yu ; Muehlenbachs, Atis ; Goldsmith, Cynthia S. ; Zhao, Hui ; Petersen, Brett ; McCollum, Andrea M. ; Reynolds, Mary G.
• Description:
  We describe a burn patient who developed skin lesions on her skin-graft harvest and skin-graft recipient (burn) sites. Orf virus infection was confirmed by a combination of diagnostic assays, including molecular tests, immunohistochemical analysis, pathologic analysis, and electron microscopy. DNA sequence analysis grouped this orf virus isolate among isolates from India. Although no definitive source of infection was determined from this case, this is the first reported case of orf virus infection in a skin graft harvest. Skin graft recipients with exposures to animals may be at risk for this viral infection.
• Subjects:
  Burns Child, Preschool DNA, Viral Ecthyma, Contagious Female Humans Orf Virus Sequence Analysis, DNA Skin Skin Transplantation
• Source:
  J Infect Dis. 214(8):1171-1174.
• Pubmed ID:
  27456708
• Pubmed Central ID:
  PMC5663183
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  214
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:01e94deff5e6bc1d47c6206ea0e79877ed6499c43bc05981420bb39fcc16a3e0
• Download URL:
  https://stacks.cdc.gov/view/cdc/49441/cdc_49441_DS1.pdf
• File Type:
  [PDF - 556.77 KB ]