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The Number of Interviews Needed to Yield New Syphilis and Human Immunodeficiency Virus Cases Among Partners of People Diagnosed With Syphilis, North Carolina, 2015
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Aug 2017
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Source: Sex Transm Dis. 44(8):451-456.
Details:
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Alternative Title:Sex Transm Dis
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Personal Author:
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Description:Objective
Compare syphilis investigation yield among patient groups using number needed to interview.
Goal
To increase investigation efficiency.
Study Design
Retrospective review of North Carolina 2015 syphilis investigations, using the number of cases needed to interview (NNTI) and the number of cases and contacts needed to interview (TNTI) to compare yield of new syphilis and HIV diagnoses between patient groups.
Results
We reviewed 1,646 early syphilis cases and 2,181 contacts; these yielded 241 new syphilis cases (NNTI=6.9; TNTI=16.4) and 38 new HIV cases (NNTI=43). Interviews of women (prevalence difference (PD)=6%, 95% CI 12–16), patients <30 years old (PD=5%, 95% CI 1–8), and patients with titer >1:16 (PD=5%, 95% CI 1–9) yielded more new syphilis cases in our adjusted model; no other patient factors increased investigation yield.
Conclusions
NNTI and TNTI are useful measures of efficiency. Prioritizing early syphilis investigation by gender, RPR titer, and age provides small increases in efficiency; no other factors increased efficiency.
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Pubmed ID:28703722
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Pubmed Central ID:PMC5644378
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Volume:44
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Issue:8
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