Morbidity and Mortality Weekly Report (MMWR): Surveillance Summaries, September 2017 / Vol. 66 / No. SS-15

Details

• Alternative Title:
  BRCA Genetic Testing and Receipt of Preventive Interventions Among Women Aged 18–64 Years with Employer-Sponsored Health Insurance in Nonmetropolitan and Metropolitan Areas -- United States, 2009–2014
• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR): Surveillance Summaries
• Personal Author:
  Kolor, Katherine ; Chen, Zhuo ; Grosse, Scott D. ; Rodriguez, Juan L. ; Green, Ridgely Fisk ; Dotson, W. David ; Bowen, M. Scott; ; Lynch, Julie A. ; Khoury, Muin J.
• Corporate Authors:
  Centers for Disease Control and Prevention (U.S.). Office of Public Health Genomics ; National Center on Birth Defects and Developmental Disabilities (Centers for Disease Control and Prevention) ; National Center for Chronic Disease Prevention and Health Promotion (U.S.). Division of Cancer Prevention and Control
• Description:
  Genetic testing for breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) gene mutations can identify women at increased risk for breast and ovarian cancer. These testing results can be used to select preventive interventions and guide treatment. Differences between nonmetropolitan and metropolitan populations in rates of BRCA testing and receipt of preventive interventions after testing have not previously been examined. Medical claims data from Truven Health Analytics MarketScan Commercial Claims and Encounters databases were used to estimate rates of BRCA testing and receipt of preventive interventions after BRCA testing among women aged 18-64 years with employer-sponsored health insurance in metropolitan and nonmetropolitan areas of the United States, both nationally and regionally. From 2009 to 2014, BRCA testing rates per 100,000 women aged 18-64 years with employer-sponsored health insurance increased 2.3 times (102.7 to 237.8) in metropolitan areas and 3.0 times (64.8 to 191.3) in nonmetropolitan areas. The relative difference in BRCA testing rates between metropolitan and nonmetropolitan areas decreased from 37% in 2009 (102.7 versus 64.8) to 20% in 2014 (237.8 versus 191.3). The relative difference in BRCA testing rates between metropolitan and nonmetropolitan areas decreased more over time in younger women than in older women and decreased in all regions except the West. Receipt of preventive services 90 days after BRCA testing in metropolitan versus nonmetropolitan areas throughout the period varied by service: the percentage of women who received a mastectomy was similar, the percentage of women who received magnetic resonance imaging of the breast was lower in nonmetropolitan areas (as low as 5.8% in 2014 to as high as 8.2% in 2011) than metropolitan areas (as low as 7.3% in 2014 to as high as 10.3% in 2011), and the percentage of women who received mammography was lower in nonmetropolitan areas in earlier years but was similar in later years.
  
  Suggested citation for this article: Kolor K, Chen Z, Grosse SD, et al. BRCA Genetic Testing and Receipt of Preventive Interventions Among Women Aged 18–64 Years with Employer-Sponsored Health Insurance in Nonmetropolitan and Metropolitan Areas — United States, 2009–2014. MMWR Surveill Summ 2017;66(No. SS-15):1–11. DOI: http://dx.doi.org/10.15585/mmwr.ss6615a1.
  
  
• Subjects:
  Breast Neoplasms / Diagnosis Breast Neoplasms / Prevention & Control Genes, BRCA1 Genes, BRCA2 Genetic Testing / Methods Health Benefit Plans, Employee Ovarian Neoplasms / Diagnosis Ovarian Neoplasms / Prevention & Control Rural Health Urban Health
• Source:
  Morbidity and Mortality Weekly Report (MMWR): Surveillance Summaries, 2017; v. 66, no. 15
• Series:
  Surveillance Summaries: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.ss6615a1
• ISSN:
  1546-0738 (print) ; 1545-8636 (digital)
• Pubmed ID:
  28880857
• Pubmed Central ID:
  PMC5879728
• Document Type:
  Journal Issue
• Genre:
  Statistics
• Place as Subject:
  United States
• Pages in Document:
  11 pdf pages
• Volume:
  66
• Issue:
  15
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:050cdb04760cee5aae5b0225f2f0905cb8bf1bd7d1a1c84a00bd46c7b373a61a56e1d7040ca735b254bbd3cf4622ed80021f0747ab2dae395b60debf85475324
• Download URL:
  https://stacks.cdc.gov/view/cdc/47994/cdc_47994_DS1.pdf
• File Type:
  [PDF - 271.84 KB ]