Details:

Alternative Title:
PLoS One
Publisher's site:
http://dx.doi.org/10.1371/journal.pone.0181696
Personal Author:
McKee, Clifton D. ; Kosoy, Michael Y. ; Bai, Ying ; Osikowicz, Lynn M. ; Franka, Richard ; ... More +
McKee, Clifton D. ; Kosoy, Michael Y. ; Bai, Ying ; Osikowicz, Lynn M. ; Franka, Richard ; Gilbert, Amy T. ; Boonmar, Sumalee ; Rupprecht, Charles E. ; Peruski, Leonard F. Less -
Description:
Bartonellae are phylogenetically diverse, intracellular bacteria commonly found in mammals. Previous studies have demonstrated that bats have a high prevalence and diversity of Bartonella infections globally. Isolates (n = 42) were obtained from five bat species in four provinces of Thailand and analyzed using sequences of the citrate synthase gene (gltA). Sequences clustered into seven distinct genogroups; four of these genogroups displayed similarity with Bartonella spp. sequences from other bats in Southeast Asia, Africa, and Eastern Europe. Thirty of the isolates representing these seven genogroups were further characterized by sequencing four additional loci (ftsZ, nuoG, rpoB, and ITS) to clarify their evolutionary relationships with other Bartonella species and to assess patterns of diversity among strains. Among the seven genogroups, there were differences in the number of sequence variants, ranging from 1-5, and the amount of nucleotide divergence, ranging from 0.035-3.9%. Overall, these seven genogroups meet the criteria for distinction as novel Bartonella species, with sequence divergence among genogroups ranging from 6.4-15.8%. Evidence of intra- and intercontinental phylogenetic relationships and instances of homologous recombination among Bartonella genogroups in related bat species were found in Thai bats.
Subject:
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Animals
Bacterial Proteins
Bartonella
Bartonella Infections
Biodiversity
Chiroptera
Citrate (si)-Synthase
Phylogeny
Polymorphism, Genetic

Source:
PLoS One. 12(7).
Pubmed ID:
28727827
Pubmed Central ID:
PMC5519213
Document Type:
Journal Article
Place as Subject:
Thailand
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f1d1a62d3115ac31b6f0d2aa32f8a3dc97f5fc28a5716492caa440647729b128
File Type:

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