Association Between Cardiovascular Risk and Depressive Symptoms Among People with Serious Mental Illness

Details

• Alternative Title:
  J Nerv Ment Dis
• Personal Author:
  Naslund, John A. ; Aschbrenner, Kelly A. ; Pratt, Sarah I. ; Lohman, Matthew C. ; Scherer, Emily A. ; McHugo, Gregory J. ; Marsch, Lisa A. ; Unützer, Jürgen ; Bartels, Stephen J.
• Description:
  Depressive symptoms have debilitating effects on the physical health and functioning of people with serious mental illness. We examined change in depressive symptoms among overweight and obese adults with serious mental illness (n = 343) using data combined from two randomized trials comparing the 12-month In SHAPE program to a gym membership control condition. In SHAPE consists of a gym membership, weekly individual meetings with a fitness trainer, and instruction on healthy eating and nutrition. Depressive symptoms were measured at baseline, 3, 6, and 12 months. Change in depressive symptoms did not differ between groups, but depressive symptoms decreased over time across the entire sample (p = 0.045). At 12 months, reduced depressive symptoms were associated with clinically significant improved cardiorespiratory fitness (p = 0.030), 10% or more weight loss (p = 0.044), and cardiovascular risk reduction (p = 0.028) across both groups. Our findings suggest that participation in health promotion programs resulting in cardiovascular risk reduction may be associated with reduced depressive symptoms.
• Subjects:
  Adult Article Bipolar Disorder Cardiovascular Diseases Cardiovascular Risk Depression Depressive Disorder, Major Female Fitness Health Promotion Humans Lifestyle Intervention Male Mental Health Middle Aged Obesity Outcome Assessment (Health Care) Overweight Physical Fitness Psychotic Disorders Risk Reduction Behavior Schizophrenia Serious Mental Illness Weight Loss

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• Source:
  J Nerv Ment Dis. 205(8):634-640.
• Pubmed ID:
  28240625
• Pubmed Central ID:
  PMC5533633
• Document Type:
  Journal Article
• Funding:
  R01 MH078052/MH/NIMH NIH HHS/United States ; T32 MH073553/MH/NIMH NIH HHS/United States ; R01 MH089811/MH/NIMH NIH HHS/United States ; P30 DA029926/DA/NIDA NIH HHS/United States ; U48 DP005018/DP/NCCDPHP CDC HHS/United States ; U48 DP001935/DP/NCCDPHP CDC HHS/United States ; R01 DD000140/DD/NCBDD CDC HHS/United States
• Volume:
  205
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:26cae3addc44eafdce8c5f0f58e6cd7673a468a0f49fdf335bee87fa1aff8b6e
• Download URL:
  https://stacks.cdc.gov/view/cdc/47216/cdc_47216_DS1.pdf
• File Type:
  [PDF - 340.59 KB ]