ROTATING NIGHT SHIFT WORK, SLEEP, AND COLORECTAL ADENOMA IN WOMEN

Details

• Alternative Title:
  Int J Colorectal Dis
• Personal Author:
  Devore, Elizabeth E. ; Massa, Jennifer ; Papantoniou, Kyriaki ; Schernhammer, Eva S. ; Wu, Kana ; Zhang, Xuehong ; Willett, Walter C. ; Fuchs, Charles S. ; Chan, Andrew T. ; Ogino, Shuji ; Giovannucci, Edward ; Wei, Esther K.
• Description:
  Purpose
  
  To investigate the associations of rotating night shift work history and sleep duration with risk of colorectal adenoma.
  
  Methods
  
  We evaluated 56,275 cancer-free participants of the Nurses’ Health Study II, who had their first colonoscopy or sigmoidoscopy between 1991 and 2011; rotating night shift work and sleep duration were reported by mailed questionnaire. Multivariable-adjusted logistic regression was used to estimate relative risks (RR) of colorectal adenoma, with 95% confidence intervals (CI), across categories of rotating night shift work history (none, 1–4, 5–9, and ≥10 years) and sleep duration (≤5, 6, 7, 8, and ≥9 hours/day).
  
  Results
  
  We found no association between duration of rotating night shift work and occurrence of colorectal adenoma (p-trend across shift work categories=0.5). Women with the longest durations of rotating night shift work (≥10 years) had a similar risk of adenoma compared to women without a history of rotating night shift work (multivariable-adjusted RR: 0.96, 95% CI: 0.83–1.11). Similarly, there were no associations of shorter or longer sleep durations with adenoma risk (p-trend=0.2 across sleep durations of ≤5 through 7 hours/day, and p-trend=0.5 across sleep durations of 7 through ≥9 hours/day). Results were similar when we examined associations according to adenoma location and subtype.
  
  Conclusions
  
  Our results do not support an association between rotating night shift work or sleep duration and risk of colorectal adenoma in women.
  
  
• Subjects:
  Adenoma Adult Article Colonoscopy Colorectal Neoplasms Female Humans Middle Aged Polyps Risk Risk Factors Rotating Night Shift Work Shift Work Schedule Sleep Women

  More +
• Source:
  Int J Colorectal Dis. 32(7):1013-1018.
• Pubmed ID:
  28097381
• Pubmed Central ID:
  PMC5474168
• Document Type:
  Journal Article
• Funding:
  R35 CA197735/CA/NCI NIH HHS/United States ; R01 CA118553/CA/NCI NIH HHS/United States ; R01 OH009803/OH/NIOSH CDC HHS/United States ; UL1 TR001863/TR/NCATS NIH HHS/United States ; UM1 CA176726/CA/NCI NIH HHS/United States ; R21 OH010204/OH/NIOSH CDC HHS/United States ; P50 CA127003/CA/NCI NIH HHS/United States
• Volume:
  32
• Issue:
  7
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:1a244818fc2ede41b8fe6a3e406c0cc4ba8c52d5cb2b2c72a700e9a5030847bd
• Download URL:
  https://stacks.cdc.gov/view/cdc/46327/cdc_46327_DS1.pdf
• File Type:
  [PDF - 80.00 KB ]