Botulism mortality in the USA, 1975–2009

Details

• Alternative Title:
  Botulinum J
• Personal Author:
  Jackson, Kelly A. ; Mahon, Barbara E. ; Copeland, John ; Fagan, Ryan P.
• Description:
  Botulism had mortality rates >60% before the 1950s. We reviewed confirmed botulism cases in the USA during 1975-2009 including infant, foodborne, wound, and other/unknown acquisition categories, and calculated mortality ratios. We created a multivariate logistic regression model for non-infant cases (foodborne, wound, and other/unknown). Overall mortality was 3.0% with 109 botulism-related deaths among 3,618 botulism cases [18 (<1%) deaths among 2,352 infant botulism cases, 61 (7.1%) deaths among 854 foodborne botulism cases, 18 (5.0%) deaths among 359 wound botulism cases, and 12 (22.6%) deaths among 53 other/unknown botulism cases]. Mortality among all cases increased with age; it was lowest among infants (0.8%) and highest among persons ≥80 years old (34.4%). Toxin type F had higher mortality (13.8%) than types A, B, or E (range, 1.4% to 4.1%). Efforts to reduce botulism mortality should target non-infant transmission categories and older adults.
• Subjects:
  Age Groups Article Botulism Food Infant Mortality USA
• Source:
  Botulinum J. 3(1):6-17.
• Pubmed ID:
  28603554
• Pubmed Central ID:
  PMC5460764
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  3
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d43101f45ebe9868bc31488c2ec2e8ad2d16b3cc166905650f133e3e0e27112e
• Download URL:
  https://stacks.cdc.gov/view/cdc/46319/cdc_46319_DS1.pdf
• File Type:
  [PDF - 117.23 KB ]