Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin1

Bukreyeva, Iryna; Angoulvant, Adela; Bendib, Inès; Gagnard, Jean-Charles; Bourhis, Jean-Henri; Dargère, Sylvie; Bonhomme, Julie; Thellier, Marc; Gachot, Bertrand; Wyplosz, Benjamin

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Enterocytozoon bieneusi Microsporidiosis in Stem Cell Transplant Recipients Treated with Fumagillin1

Supporting Files Public Domain

Jun 2017
By Bukreyeva, Iryna ; Angoulvant, Adela ; Bendib, Inès ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Bukreyeva, Iryna ; Angoulvant, Adela ; Bendib, Inès ; Gagnard, Jean-Charles ; Bourhis, Jean-Henri ; Dargère, Sylvie ; Bonhomme, Julie ; Thellier, Marc ; Gachot, Bertrand ; Wyplosz, Benjamin
Description:

Enterocytozoon bieneusi microsporidiosis is an emerging disease in immunocompromised patients. We report 2 cases of this disease in allogeneic hematopoietic stem cell transplant patients successfully treated with fumagillin. Thrombocytopenia occurred but without major adverse events. Modifications of immunosuppression could be avoided when E. bieneusi is rapidly identified and fumagillin therapy is started promptly.
Subjects:

Adult Antifungal Agents Cyclohexanes Enterocytozoon Fatty Acids, Unsaturated Female Hematopoietic Stem Cell Transplantation Humans Immunosuppressive Agents Leukemia, Myeloid Male Microsporidiosis Middle Aged Mycophenolic Acid Platelet Count Prednisone Sesquiterpenes Thrombocytopenia Treatment Outcome
Source:

Emerg Infect Dis. 23(6):1039-1041.
Pubmed ID:

28518017
Pubmed Central ID:

PMC5443440
Document Type:

Journal Article
Volume:

23
Issue:

6
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:7b74d70036550581502027def7ff783628787f65099cbf92748eb0462ccc0247
Download URL:

https://stacks.cdc.gov/view/cdc/45981/cdc_45981_DS1.pdf
File Type:

[PDF - 404.19 KB ]

File Language:

English

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