Nicotine, Aerosol Particles, Carbonyls and Volatile Organic Compounds in Tobacco- and Menthol-Flavored e-Cigarettes

Details

• Journal Article:
  Environmental Health: A Global Access Science Source
• Personal Author:
  Lee, Mi-Sun ; LeBouf, Ryan F. ; Son, Youn-Suk ; Koutrakis, Petros ; Christiani, David C.
• Description:
  Background: We aimed to assess the content of electronic cigarette (EC) emissions for five groups of potentially toxic compounds that are known to be present in tobacco smoke: nicotine, particles, carbonyls, volatile organic compounds (VOCs), and trace elements by flavor and puffing time. Methods: We used ECs containing a common nicotine strength (1.8%) and the most popular flavors, tobacco and menthol. An automatic multiple smoking machine was used to generate EC aerosols under controlled conditions. Using a dilution chamber, we targeted nicotine concentrations similar to that of exposure in a general indoor environment. The selected toxic compounds were extracted from EC aerosols into a solid or liquid phase and analyzed with chromatographic and spectroscopic methods. Results: We found that EC aerosols contained toxic compounds including nicotine, fine and nanoparticles, carbonyls, and some toxic VOCs such as benzene and toluene. Higher mass and number concentrations of aerosol particles were generated from tobacco-flavored ECs than from menthol-flavored ECs. Conclusion: We found that diluted machine-generated EC aerosols contain some pollutants. These findings are limited by the small number of ECs tested and the conditions of testing. More comprehensive research on EC exposure extending to more brands and flavor compounds is warranted. [Description provided by NIOSH]
• Subjects:
  Aerosols Air Pollution Benzene Chromatography Electrical Equipment And Supplies Electronic Nicotine Delivery Systems Flavoring Agents Menthol Nanoparticles Nicotine Occupational Health Particulate Matter Safety Smokers Tobacco Products Toluene Volatile Organic Compounds

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• Keywords:
  Author Keywords: Carbonyls; Nicotine; Particles; VOCs In E-cigarette Emissions Nicotine; Aerosol Particles; Particulates; Carbonyls; VOCs; Volatile Organic Compounds; Tobacco; Cigarette Smoking; Electronic Devices; Emission Sources; Aerosols; Flavorings; Chromatographic Analysis; Nanoparticles; Benzene; Toluenes;
• Source:
  Environ Health 2017 Apr; 16:42
• ISSN:
  1476-069X
• Pubmed ID:
  28449666
• Pubmed Central ID:
  PMC5406907
• Document Type:
  Text
• Funding:
  P30 ES000002/ES/NIEHS NIH HHS/United States
• Genre:
  Journal Article
• Place as Subject:
  Massachusetts ; OSHA Region 1 ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  RHD - Respiratory Health Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  10 pdf pages
• Volume:
  16
• NIOSHTIC Number:
  nn:20049834
• Contact Point Address:
  David C. Christiani, Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard T. H. Chan School of Public Health, 665 Huntington Ave, Building I Room 1401, Boston MA 02115
• Email:
  dchris@hsph.harvard.edu
• CAS Registry Number:
  Benzene (CAS RN 71-43-2) ; Toluene (CAS RN 108-88-3)
• Federal Fiscal Year:
  2017
• Peer Reviewed:
  True
• Collection(s):
  National Institute for Occupational Safety and Health CDC Public Access
• Main Document Checksum:
  urn:sha-512:6b30e52807680130451159357f2aa20ccdebe52e916236a1e62d13cf0516d9d1a8fc225c3d77c0b2866653490dfb47e87aeae34781aae03b302bfb03bceb491a
• Download URL:
  https://stacks.cdc.gov/view/cdc/45428/cdc_45428_DS1.pdf
• File Type:
  [PDF - 603.31 KB ]